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VMT9_MYXVL
ID   VMT9_MYXVL              Reviewed;         509 AA.
AC   P08073;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 2.
DT   29-SEP-2021, entry version 96.
DE   RecName: Full=Kelch repeat protein M-T9;
DE   AltName: Full=M9-R polypeptide;
GN   OrderedLocusNames=m009L;
OS   Myxoma virus (strain Lausanne) (MYXV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Leporipoxvirus.
OX   NCBI_TaxID=31530;
OH   NCBI_TaxID=9986; Oryctolagus cuniculus (Rabbit).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2173255; DOI=10.1016/0042-6822(90)90129-f;
RA   Upton C., Macen J.L., Wishart D.S., McFadden G.;
RT   "Myxoma virus and malignant rabbit fibroma virus encode a serpin-like
RT   protein important for virus virulence.";
RL   Virology 179:618-631(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10562494; DOI=10.1006/viro.1999.0001;
RA   Cameron C., Hota-Mitchell S., Chen L., Barrett J.W., Cao J.-X.,
RA   Macaulay C., Willer D.O., Evans D.H., McFadden G.;
RT   "The complete DNA sequence of myxoma virus.";
RL   Virology 264:298-318(1999).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-235.
RX   PubMed=3029424; DOI=10.1128/jvi.61.4.1271-1275.1987;
RA   Upton C., Macen J.L., McFadden G.;
RT   "Mapping and sequencing of a gene from myxoma virus that is related to
RT   those encoding epidermal growth factor and transforming growth factor
RT   alpha.";
RL   J. Virol. 61:1271-1275(1987).
CC   -!- SIMILARITY: Belongs to the poxviruses Kelch family. {ECO:0000305}.
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DR   EMBL; M15806; AAA46627.1; -; Genomic_DNA.
DR   EMBL; AF170726; AAF14897.1; -; Genomic_DNA.
DR   PIR; A36418; WMVZMX.
DR   RefSeq; NP_051723.1; NC_001132.2.
DR   SMR; P08073; -.
DR   GeneID; 932145; -.
DR   KEGG; vg:932145; -.
DR   Proteomes; UP000000867; Genome.
DR   Gene3D; 2.120.10.80; -; 1.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR024182; Vaccinia_A55R.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 3.
DR   PIRSF; PIRSF003716; VAC_F3L; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 3.
DR   SUPFAM; SSF117281; SSF117281; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   3: Inferred from homology;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..509
FT                   /note="Kelch repeat protein M-T9"
FT                   /id="PRO_0000119171"
FT   DOMAIN          15..79
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   REPEAT          274..320
FT                   /note="Kelch 1"
FT   REPEAT          321..368
FT                   /note="Kelch 2"
FT   REPEAT          370..415
FT                   /note="Kelch 3"
FT   REPEAT          416..463
FT                   /note="Kelch 4"
FT   REPEAT          465..509
FT                   /note="Kelch 5"
SQ   SEQUENCE   509 AA;  57931 MW;  1CAFC32EFB26D71F CRC64;
     MSRTLLRFLE DGAMSDVTVV AGDSTFLGHK VILSLHSDYF YRLFNGDFTS PDTVTLDATD
     DAVRTVFTYM YAGCDGLNDR TIDDLQSIIV LADYLGITKL VDECVRRIVS KVDVLNCVGV
     YTFAETYHIT DLQRAAKTFL TELLGSKEAF EELSQDDAVI ALRETRNIVD RRSILRAILL
     WVRKCPDRIE QLKVLVAAVD DVDDDDNVYT IYERYAEELK DMIACPLSYN CVVVVDRDRY
     VRLINPDTLW SKRVTYIRKR AIGDRFTVVC MNNVLYCLGG TLDGAPTCDV LAYDLLTNEY
     SLMPEMGHYR RNASACIVNG YIYVVGGVDE ENRLIGSVEY WQPGMEEWHD APYLQANVET
     ATVCYRNELW IVGGTVDLYH PTFISAVKKL TDNRWMSMEP LPEPRSGATT VVYNNRLYCI
     GGRIHGGAYT NHVYNYLDES RTWERVGDMA NVRRNPSCCV YNKAIYVLGG NTNAVEKYNG
     WKWQEVGNIS TYPACNNTAY PFFYTNDEI
 
 
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