VMT9_MYXVL
ID VMT9_MYXVL Reviewed; 509 AA.
AC P08073;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 2.
DT 29-SEP-2021, entry version 96.
DE RecName: Full=Kelch repeat protein M-T9;
DE AltName: Full=M9-R polypeptide;
GN OrderedLocusNames=m009L;
OS Myxoma virus (strain Lausanne) (MYXV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Leporipoxvirus.
OX NCBI_TaxID=31530;
OH NCBI_TaxID=9986; Oryctolagus cuniculus (Rabbit).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2173255; DOI=10.1016/0042-6822(90)90129-f;
RA Upton C., Macen J.L., Wishart D.S., McFadden G.;
RT "Myxoma virus and malignant rabbit fibroma virus encode a serpin-like
RT protein important for virus virulence.";
RL Virology 179:618-631(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10562494; DOI=10.1006/viro.1999.0001;
RA Cameron C., Hota-Mitchell S., Chen L., Barrett J.W., Cao J.-X.,
RA Macaulay C., Willer D.O., Evans D.H., McFadden G.;
RT "The complete DNA sequence of myxoma virus.";
RL Virology 264:298-318(1999).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-235.
RX PubMed=3029424; DOI=10.1128/jvi.61.4.1271-1275.1987;
RA Upton C., Macen J.L., McFadden G.;
RT "Mapping and sequencing of a gene from myxoma virus that is related to
RT those encoding epidermal growth factor and transforming growth factor
RT alpha.";
RL J. Virol. 61:1271-1275(1987).
CC -!- SIMILARITY: Belongs to the poxviruses Kelch family. {ECO:0000305}.
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DR EMBL; M15806; AAA46627.1; -; Genomic_DNA.
DR EMBL; AF170726; AAF14897.1; -; Genomic_DNA.
DR PIR; A36418; WMVZMX.
DR RefSeq; NP_051723.1; NC_001132.2.
DR SMR; P08073; -.
DR GeneID; 932145; -.
DR KEGG; vg:932145; -.
DR Proteomes; UP000000867; Genome.
DR Gene3D; 2.120.10.80; -; 1.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR024182; Vaccinia_A55R.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF003716; VAC_F3L; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 3.
DR SUPFAM; SSF117281; SSF117281; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
DR PROSITE; PS50097; BTB; 1.
PE 3: Inferred from homology;
KW Kelch repeat; Reference proteome; Repeat.
FT CHAIN 1..509
FT /note="Kelch repeat protein M-T9"
FT /id="PRO_0000119171"
FT DOMAIN 15..79
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT REPEAT 274..320
FT /note="Kelch 1"
FT REPEAT 321..368
FT /note="Kelch 2"
FT REPEAT 370..415
FT /note="Kelch 3"
FT REPEAT 416..463
FT /note="Kelch 4"
FT REPEAT 465..509
FT /note="Kelch 5"
SQ SEQUENCE 509 AA; 57931 MW; 1CAFC32EFB26D71F CRC64;
MSRTLLRFLE DGAMSDVTVV AGDSTFLGHK VILSLHSDYF YRLFNGDFTS PDTVTLDATD
DAVRTVFTYM YAGCDGLNDR TIDDLQSIIV LADYLGITKL VDECVRRIVS KVDVLNCVGV
YTFAETYHIT DLQRAAKTFL TELLGSKEAF EELSQDDAVI ALRETRNIVD RRSILRAILL
WVRKCPDRIE QLKVLVAAVD DVDDDDNVYT IYERYAEELK DMIACPLSYN CVVVVDRDRY
VRLINPDTLW SKRVTYIRKR AIGDRFTVVC MNNVLYCLGG TLDGAPTCDV LAYDLLTNEY
SLMPEMGHYR RNASACIVNG YIYVVGGVDE ENRLIGSVEY WQPGMEEWHD APYLQANVET
ATVCYRNELW IVGGTVDLYH PTFISAVKKL TDNRWMSMEP LPEPRSGATT VVYNNRLYCI
GGRIHGGAYT NHVYNYLDES RTWERVGDMA NVRRNPSCCV YNKAIYVLGG NTNAVEKYNG
WKWQEVGNIS TYPACNNTAY PFFYTNDEI