ID   VN1R5_GORGO             Reviewed;         357 AA.
AC   Q7YRP1;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Vomeronasal type-1 receptor 5;
DE   AltName: Full=V1r-like receptor 5;
GN   Name=VN1R5; Synonyms=V1RL5;
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Gorilla.
OX   NCBI_TaxID=9595;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=12826614; DOI=10.1073/pnas.1331721100;
RA   Zhang J., Webb D.M.;
RT   "Evolutionary deterioration of the vomeronasal pheromone transduction
RT   pathway in catarrhine primates.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:8337-8341(2003).
CC   -!- FUNCTION: Putative pheromone receptor.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000305}.
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DR   EMBL; AY312475; AAP85611.1; -; Genomic_DNA.
DR   RefSeq; XP_004028761.1; XM_004028712.2.
DR   AlphaFoldDB; Q7YRP1; -.
DR   STRING; 9593.ENSGGOP00000002388; -.
DR   Ensembl; ENSGGOT00000002439; ENSGGOP00000002388; ENSGGOG00000002427.
DR   GeneID; 101153670; -.
DR   KEGG; ggo:101153670; -.
DR   eggNOG; ENOG502SNRJ; Eukaryota.
DR   GeneTree; ENSGT01030000234553; -.
DR   HOGENOM; CLU_058641_0_0_1; -.
DR   InParanoid; Q7YRP1; -.
DR   OMA; CKVIVFL; -.
DR   OrthoDB; 1390012at2759; -.
DR   Proteomes; UP000001519; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR   InterPro; IPR004072; Vmron_rcpt_1.
DR   PANTHER; PTHR24062; PTHR24062; 1.
DR   Pfam; PF03402; V1R; 2.
DR   PRINTS; PR01534; VOMERONASL1R.
PE   3: Inferred from homology;
KW   Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane;
KW   Pheromone response; Receptor; Reference proteome; Transducer;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..357
FT                   /note="Vomeronasal type-1 receptor 5"
FT                   /id="PRO_0000070219"
FT   TOPO_DOM        1..3
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        4..24
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        25..52
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..73
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        74..81
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        103..130
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        131..151
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        152..163
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..184
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        185..269
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        270..290
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        291..300
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        301..321
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        322..357
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        297
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   357 AA;  41016 MW;  F373288FBD5B7D57 CRC64;
     MLKLVIIENM AEIMLFSLDL LLFSTDILCF NFPSKMIKLP GFITIQIFFY PQASFGISAN
     TILFLFHIFT FVFSHRSKSI DMIISHLSLI HILLLFTQAI LVSLDFFGSQ NTQDDLRCKV
     IVFLNKVMRG LSICTPCLLN VLQAIISPSI FSLAKLKHPS ASHILGFFLF SWVLNMFIGV
     IFCCTLWLPP VKWGQSSVCH TALFLFAHEL HPQETVFHTN DFEGCHLYRV HGPLKRLHGD
     YFIQTIRGYL SAFTQPACPP VSPVKRASQT ILLLVSFVFI YWVDFMFSFS RGVTWINDSL
     LVWFQVIVAN SYATISPLML IYADNQIFKT LQMLWFKYLS PPKLMLKFNR QCGSTKK