VNB_INBBE
ID VNB_INBBE Reviewed; 99 AA.
AC P27908;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 07-OCT-2020, entry version 58.
DE RecName: Full=Glycoprotein NB;
GN Name=NB;
OS Influenza B virus (strain B/Beijing/1/1987).
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC Insthoviricetes; Articulavirales; Orthomyxoviridae; Betainfluenzavirus.
OX NCBI_TaxID=11525;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=1984652; DOI=10.1016/0042-6822(91)90031-6;
RA Burmeister W.P., Daniels R.S., Dayan S., Gagnon J., Cusack S.,
RA Ruigrok R.W.;
RT "Sequence and crystallization of influenza virus B/Beijing/1/87
RT neuraminidase.";
RL Virology 180:266-272(1991).
CC -!- FUNCTION: Putative viral proton channel. May play a role in virus entry
CC (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Dimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305}; Single-pass type
CC III membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the influenza viruses type B glycoprotein NB
CC family. {ECO:0000305}.
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DR EMBL; M54967; AAA43732.1; -; Genomic_RNA.
DR PIR; A38520; VGIVB1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0044385; C:integral to membrane of host cell; IEA:UniProtKB-KW.
DR GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:ion channel activity; IEA:UniProtKB-KW.
DR GO; GO:0039707; P:pore formation by virus in membrane of host cell; IEA:UniProtKB-KW.
DR GO; GO:0051259; P:protein complex oligomerization; IEA:UniProtKB-KW.
DR InterPro; IPR007288; InfluenzaB_glycoprotein_NB.
DR Pfam; PF04159; NB; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Hydrogen ion transport; Ion channel; Ion transport; Membrane;
KW Signal-anchor; Transmembrane; Transmembrane helix; Transport;
KW Viral ion channel; Virion.
FT CHAIN 1..99
FT /note="Glycoprotein NB"
FT /id="PRO_0000078904"
FT TOPO_DOM 1..18
FT /note="Virion surface"
FT /evidence="ECO:0000255"
FT TRANSMEM 19..40
FT /note="Helical; Signal-anchor for type III membrane
FT protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 41..99
FT /note="Intravirion"
FT /evidence="ECO:0000255"
FT CARBOHYD 3
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
FT CARBOHYD 7
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
SQ SEQUENCE 99 AA; 10893 MW; EA0798A19081339D CRC64;
MNNATFNYTN VNPISHIRGS VIITICVSFT VILTVFGYIA KIFIKNNCTN NDIGLRERIK
CSGCEPLCNK RDDISSPRTG VDIPSFILPG LNLSESTPN