ID   VNB_INBME               Reviewed;          99 AA.
AC   P67909; P16194; P16198;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   07-OCT-2020, entry version 44.
DE   RecName: Full=Glycoprotein NB;
GN   Name=NB;
OS   Influenza B virus (strain B/Memphis/6/1986).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Insthoviricetes; Articulavirales; Orthomyxoviridae; Betainfluenzavirus.
OX   NCBI_TaxID=11538;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1695410; DOI=10.1016/0042-6822(90)90523-t;
RA   Air G.M., Laver W.G., Luo M., Stray S.J., Legrone G., Webster R.G.;
RT   "Antigenic, sequence, and crystal variation in influenza B neuraminidase.";
RL   Virology 177:578-587(1990).
CC   -!- FUNCTION: Putative viral proton channel. May play a role in virus entry
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Dimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305}; Single-pass type
CC       III membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the influenza viruses type B glycoprotein NB
CC       family. {ECO:0000305}.
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DR   EMBL; M30634; AAA43736.1; -; Genomic_RNA.
DR   PIR; B36825; B36825.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0044385; C:integral to membrane of host cell; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0039707; P:pore formation by virus in membrane of host cell; IEA:UniProtKB-KW.
DR   GO; GO:0051259; P:protein complex oligomerization; IEA:UniProtKB-KW.
DR   InterPro; IPR007288; InfluenzaB_glycoprotein_NB.
DR   Pfam; PF04159; NB; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Hydrogen ion transport; Ion channel; Ion transport; Membrane;
KW   Signal-anchor; Transmembrane; Transmembrane helix; Transport;
KW   Viral ion channel; Virion.
FT   CHAIN           1..99
FT                   /note="Glycoprotein NB"
FT                   /id="PRO_0000078909"
FT   TOPO_DOM        1..18
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        19..40
FT                   /note="Helical; Signal-anchor for type III membrane
FT                   protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        41..99
FT                   /note="Intravirion"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        7
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   99 AA;  10915 MW;  3909655C90813389 CRC64;
     MNNATFNYTN VNPISHIRGS VIITICVSFT VILTVFGYIA KIFTKNNCTN NDIGLRERIK
     CSGCEPFCNK RDDISSPRTG VDIPSFILPG LNLSESTPN