ID   VNS1_EHDV2              Reviewed;         552 AA.
AC   P27585;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   12-AUG-2020, entry version 39.
DE   RecName: Full=Non-structural protein NS1;
DE   AltName: Full=Hydrophobic tubular protein;
GN   Name=Segment-5;
OS   Epizootic hemorrhagic disease virus 2 (strain Alberta) (EHDV-2).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=10910;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9872; Odocoileus hemionus (Mule deer) (Cervus hemionus).
OH   NCBI_TaxID=9874; Odocoileus virginianus (White-tailed deer).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1645906; DOI=10.1016/0168-1702(91)90020-v;
RA   Nel L.H., Picard L.A., Huismans H.;
RT   "A characterization of the nonstructural protein from which the virus-
RT   specified tubules in epizootic haemorrhagic disease virus-infected cells
RT   are composed.";
RL   Virus Res. 18:219-230(1991).
CC   -!- SIMILARITY: Belongs to the orbivirus non-structural protein NS1 family.
CC       {ECO:0000305}.
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DR   EMBL; M69085; AAA43000.1; -; Genomic_RNA.
DR   EMBL; X59000; CAA41746.1; -; Genomic_RNA.
DR   SMR; P27585; -.
DR   InterPro; IPR002630; Orbi_NS1.
DR   Pfam; PF01718; Orbi_NS1; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..552
FT                   /note="Non-structural protein NS1"
FT                   /id="PRO_0000222673"
SQ   SEQUENCE   552 AA;  64554 MW;  6D4407083276B76F CRC64;
     MERFLRKFNM NSYYANHVKM FQALSPQWTC SHLRRNCLFD GVCAKQHFEE VMNRITERND
     AHAAYRLAEM AQITMLDREK VWLQCYKSFS EPYDENIAEK IQICGRELLD KYKNSDMVTK
     IDNMIKFDPT RIVLDDNFSA FPYLYIPVNY GQMVQPIRIM RYRQIGYCFY QPDAVDDWIA
     PDIYPMRRPR MEMCRQVKEA VGSCSFTGFS GPVFQIMFFP MQMLPYMENE GFAKIINRYA
     QMAVQAIFTS RLHRGERYVT QLFGECPAGE FPMHHMMLRR WEGNGRPQTL VQMRHTIAGN
     KEWQTWLLPM ILVRIAVREP ANFEYVRGFM QGRHKCQLCF LKNGCDRETF YHIDVRTSEI
     VGCSTVTQVM IGEHVDISLP VQKIKLTGTE HLGRASDHYF KYNATTGMEA LIRTAIQIHR
     WIRGTGIWEN DEWQEGIYLL ARVLLRWELS TQARSIMFRL FCFVCFGYAP RKDGTVPDWK
     DLGAFLDIIL NGTELGDDED ETGQTGIMFE LSRCVMTLAY AERIKVVTFN APECDEGAVM
     NIAQAMANMW DN