ID   VNS2_BTV1S              Reviewed;         357 AA.
AC   P32932;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   02-JUN-2021, entry version 46.
DE   RecName: Full=Non-structural protein NS2;
GN   Name=Segment-8;
OS   Bluetongue virus 1 (isolate South Africa) (BTV 1).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=10905;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=1324875; DOI=10.1016/0378-1119(92)90204-3;
RA   Wade-Evans A.M.;
RT   "The complete sequence of genome segment 8 of bluetongue virus, serotype 1,
RT   which encodes the nonstructural protein, NS2.";
RL   Gene 118:295-296(1992).
CC   -!- FUNCTION: Single-stranded RNA-binding protein.
CC   -!- SIMILARITY: Belongs to the orbivirus non-structural protein NS2 family.
CC       {ECO:0000305}.
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DR   EMBL; X58064; CAA41095.1; -; Unassigned_RNA.
DR   PIR; JC1256; JC1256.
DR   SMR; P32932; -.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR007602; BTV_NS2.
DR   InterPro; IPR037194; NS2_N.
DR   Pfam; PF04514; BTV_NS2; 1.
DR   SUPFAM; SSF110132; SSF110132; 1.
PE   3: Inferred from homology;
KW   RNA-binding.
FT   CHAIN           1..357
FT                   /note="Non-structural protein NS2"
FT                   /id="PRO_0000222674"
FT   REGION          162..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          228..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        180..199
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..258
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   357 AA;  41289 MW;  33C743E9B86674D0 CRC64;
     MEQKQRRFTK NIFVLDANGK TLCGRIAKLS SQPYCQIKIG RVIAFKPVKN PEPKGYVLNV
     PGPGAYRIQD GQDIISLMLT PHGVEATTER WEEWKFEGVS VTPMATRVQH NGVMVDAEIK
     YCKGMGIVQP YMRNDFDRNE MPDLPGVMRS NYDVRELRQK IQNERESAPR LQVQSVSPRE
     ESRWMDDDEA KVDEEAKEMI PGPSRLKKLR EARSNVFKEV EAEINWNLDE KDEEDRDERE
     DEEQVKTLSD DDEQGEDASD DEHPKTHITK EYIEKVAKQI KLKDERFMSL SSAMPPASGG
     FDRMIVTKKL KWQNVPLYCF DESSKRYELQ CVGACERVAF VSKDMSLIIL RSAFRRL