VNS2_BTV1X
ID VNS2_BTV1X Reviewed; 357 AA.
AC P10350;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1989, sequence version 1.
DT 02-JUN-2021, entry version 55.
DE RecName: Full=Non-structural protein NS2;
GN Name=Segment-8;
OS Bluetongue virus 10 (BTV 10).
OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX NCBI_TaxID=10906;
OH NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH NCBI_TaxID=9913; Bos taurus (Bovine).
OH NCBI_TaxID=9925; Capra hircus (Goat).
OH NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH NCBI_TaxID=9940; Ovis aries (Sheep).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2536152; DOI=10.1093/nar/17.1.457;
RA Hall S.J., van Dijk A.A., Huismans H.;
RT "Complete nucleotide sequence of gene segment 8 encoding non-structural
RT protein NS2 of SA bluetongue virus serotype 10.";
RL Nucleic Acids Res. 17:457-457(1989).
CC -!- FUNCTION: Single-stranded RNA-binding protein.
CC -!- SIMILARITY: Belongs to the orbivirus non-structural protein NS2 family.
CC {ECO:0000305}.
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DR EMBL; X13374; CAA31749.1; -; Genomic_RNA.
DR PIR; S02112; MNXRS2.
DR SMR; P10350; -.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR007602; BTV_NS2.
DR InterPro; IPR037194; NS2_N.
DR Pfam; PF04514; BTV_NS2; 1.
DR SUPFAM; SSF110132; SSF110132; 1.
PE 3: Inferred from homology;
KW RNA-binding.
FT CHAIN 1..357
FT /note="Non-structural protein NS2"
FT /id="PRO_0000222676"
FT REGION 163..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 41150 MW; DAC8CA75FDA09BC5 CRC64;
MEQKQRRFTK NIFVLDANAK TLCGRIAKLS SQPYCQIKIG RVIAFKPVKN PEPKGYVLNV
PGPGAYRIQD GQDIISLMLT PHGVEATTER WEEWKFEGVS VTPMATRVQH NGVMVDAEIK
YCKGMGIVQP YMRNDFDRNE MPDLPGVMRS NYDIRELRQK IKNERESAPR LQVQSVAPRE
ESRWMDDDEA KVDEEAREMI PGTSRLEKLR EARSNVFKEV AAGINWNLDE KDEEDGDERE
DEERVKTLSD DDEQGEDASD DEHPKTHITK EYVEKVAKQI KLKDERFMSL SSAMPQASGG
FDRMIVTKKL KWQNVPLYCF DESSKRYELQ CVGACERVAF VSKDMSLIIL RSAFRRL