VOZ1_ARATH
ID VOZ1_ARATH Reviewed; 486 AA.
AC Q9SGQ0; B9DG33; Q9SHP3;
DT 28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Transcription factor VOZ1;
DE AltName: Full=Protein VASCULAR PLANT ONE-ZINC FINGER 1;
DE Short=AtVOZ1;
GN Name=VOZ1; OrderedLocusNames=At1g28520; ORFNames=F1K23.24, F3M18.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], DNA-BINDING, DOMAIN, FUNCTION, AND TISSUE
RP SPECIFICITY.
RX PubMed=15295067; DOI=10.1093/pcp/pch101;
RA Mitsuda N., Hisabori T., Takeyasu K., Sato M.H.;
RT "VOZ; isolation and characterization of novel vascular plant transcription
RT factors with a one-zinc finger from Arabidopsis thaliana.";
RL Plant Cell Physiol. 45:845-854(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-478.
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [7]
RP DOMAIN VOZ.
RX DOI=10.1016/j.plantsci.2005.05.035;
RA Olsena A.N., Ernstb H.A., Leggiob L.L., Skriver K.;
RT "DNA-binding specificity and molecular functions of NAC transcription
RT factors.";
RL Plant Sci. 169:785-797(2005).
RN [8]
RP DNA-BINDING.
RX PubMed=19995345; DOI=10.1042/bj20091234;
RA Jensen M.K., Kjaersgaard T., Nielsen M.M., Galberg P., Petersen K.,
RA O'Shea C., Skriver K.;
RT "The Arabidopsis thaliana NAC transcription factor family: structure-
RT function relationships and determinants of ANAC019 stress signalling.";
RL Biochem. J. 426:183-196(2010).
RN [9]
RP INTERACTION WITH PHYB, DISRUPTION PHENOTYPE, FUNCTION, TISSUE SPECIFICITY,
RP AND INDUCTION.
RX PubMed=22904146; DOI=10.1105/tpc.112.101915;
RA Yasui Y., Mukougawa K., Uemoto M., Yokofuji A., Suzuri R., Nishitani A.,
RA Kohchi T.;
RT "The phytochrome-interacting VASCULAR PLANT ONE-ZINC FINGER1 and VOZ2
RT redundantly regulate flowering in Arabidopsis.";
RL Plant Cell 24:3248-3263(2012).
CC -!- FUNCTION: Transcriptional activator acting positively in the
CC phytochrome B signaling pathway. Functions redundantly with VOZ2 to
CC promote flowering downstream of phytochrome B (phyB). Down-regulates
CC 'FLOWERING LOCUS C' (FLC) and up-regulates 'FLOWERING LOCUS T' (FT).
CC Binds to the 38-bp cis-acting region of the AVP1 gene. Interacts with
CC phyB in the cytoplasm and is translocated to the nucleus at signal
CC transmission, where it is subjected to degradation in a phytochrome-
CC dependent manner. {ECO:0000269|PubMed:15295067,
CC ECO:0000269|PubMed:22904146}.
CC -!- SUBUNIT: Homodimer (By similarity). Interacts with phytochrome B
CC (phyB). {ECO:0000250, ECO:0000269|PubMed:22904146}.
CC -!- INTERACTION:
CC Q9SGQ0; P14713: PHYB; NbExp=4; IntAct=EBI-6306928, EBI-300727;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC Note=Cytoplasmic in darkness, and translocated to the nucleus depending
CC on the light quality mediated by phytochromes. {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Ubiquitous. Expressed in the vascular bundles of
CC various tissues, specifically in the phloem.
CC {ECO:0000269|PubMed:15295067, ECO:0000269|PubMed:22904146}.
CC -!- INDUCTION: By far-red light. {ECO:0000269|PubMed:22904146}.
CC -!- DOMAIN: The VOZ region includes a DNA-binding domain and a dimerization
CC domain. Contains an atypical zinc-finger followed by a basic region
CC structurally related to the NAC domain. {ECO:0000269|PubMed:15295067,
CC ECO:0000269|Ref.7}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype. Voz1 and voz2 double mutant
CC displays a late flowering phenotype under long-day conditions.
CC {ECO:0000269|PubMed:22904146}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF24553.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB125256; BAD17857.1; -; mRNA.
DR EMBL; AC007508; AAF24553.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC010155; AAF16771.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30986.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30987.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM58935.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM58936.1; -; Genomic_DNA.
DR EMBL; BT020261; AAV84482.1; -; mRNA.
DR EMBL; AK227014; BAE99078.1; -; mRNA.
DR EMBL; AK317006; BAH19700.1; -; mRNA.
DR PIR; B86411; B86411.
DR RefSeq; NP_001077618.1; NM_001084149.1.
DR RefSeq; NP_001319100.1; NM_001332816.1.
DR RefSeq; NP_001321335.1; NM_001332818.1.
DR RefSeq; NP_174174.1; NM_102620.5.
DR AlphaFoldDB; Q9SGQ0; -.
DR SMR; Q9SGQ0; -.
DR BioGRID; 24987; 13.
DR IntAct; Q9SGQ0; 5.
DR STRING; 3702.AT1G28520.1; -.
DR PaxDb; Q9SGQ0; -.
DR PRIDE; Q9SGQ0; -.
DR ProteomicsDB; 242701; -.
DR EnsemblPlants; AT1G28520.1; AT1G28520.1; AT1G28520.
DR EnsemblPlants; AT1G28520.2; AT1G28520.2; AT1G28520.
DR EnsemblPlants; AT1G28520.4; AT1G28520.4; AT1G28520.
DR EnsemblPlants; AT1G28520.5; AT1G28520.5; AT1G28520.
DR GeneID; 839752; -.
DR Gramene; AT1G28520.1; AT1G28520.1; AT1G28520.
DR Gramene; AT1G28520.2; AT1G28520.2; AT1G28520.
DR Gramene; AT1G28520.4; AT1G28520.4; AT1G28520.
DR Gramene; AT1G28520.5; AT1G28520.5; AT1G28520.
DR KEGG; ath:AT1G28520; -.
DR Araport; AT1G28520; -.
DR TAIR; locus:2018738; AT1G28520.
DR eggNOG; ENOG502QPN5; Eukaryota.
DR HOGENOM; CLU_037371_1_0_1; -.
DR InParanoid; Q9SGQ0; -.
DR OMA; ECKNTPL; -.
DR OrthoDB; 524603at2759; -.
DR PhylomeDB; Q9SGQ0; -.
DR PRO; PR:Q9SGQ0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SGQ0; baseline and differential.
DR Genevisible; Q9SGQ0; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR GO; GO:0009631; P:cold acclimation; IGI:CACAO.
DR GO; GO:0048574; P:long-day photoperiodism, flowering; IMP:UniProtKB.
DR GO; GO:0048578; P:positive regulation of long-day photoperiodism, flowering; IMP:UniProtKB.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
DR GO; GO:0009408; P:response to heat; IGI:CACAO.
DR GO; GO:0009651; P:response to salt stress; IEP:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IGI:CACAO.
DR InterPro; IPR039277; VOZ1/VOZ2.
DR PANTHER; PTHR33873; PTHR33873; 1.
PE 1: Evidence at protein level;
KW Activator; Cytoplasm; DNA-binding; Metal-binding; Nucleus;
KW Phytochrome signaling pathway; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..486
FT /note="Transcription factor VOZ1"
FT /id="PRO_0000420172"
FT ZN_FING 217..240
FT /note="C3H1-type; atypical"
FT /evidence="ECO:0000255"
FT REGION 208..405
FT /note="VOZ"
FT REGION 424..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 217
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255"
FT BINDING 222
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255"
FT BINDING 236
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255"
FT BINDING 240
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255"
FT CONFLICT 474
FT /note="N -> K (in Ref. 6; BAH19700)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 486 AA; 54080 MW; 9BA92951E2128858 CRC64;
MTGKRSKTNC RSASHKLFKD KAKNRVDDLQ GMLLDLQFAR KESRPTDVTL LEEQVNQMLR
EWKSELNEPS PASSLQQGGT LGSFSSDICR LLQLCDEEDD ATSKLAAPKP EPADQNLEAG
KAAVFQRGYN LVQGKSEHGL PLVDNCKDLS LAAGNNFDGT APLEYHQQYD LQQEFEPNFN
GGFNNCPSYG VVEGPIHISN FIPTICPPPS AFLGPKCALW DCPRPAQGFD WFQDYCSSFH
AALAFNEGPP GMNPVVRPGG IGLKDGLLFA ALSAKAGGKD VGIPECEGAA TAKSPWNAPE
LFDLTVLESE TLREWLFFDK PRRAFESGNR KQRSLPDYNG RGWHESRKQI MVEFGGLKRS
YYMDPQPLHH FEWHLYEYEI NKCDACALYR LELKLVDGKK TSKGKVSNDS VADLQKQMGR
LTAEFPPENN TTNTTNNNKR CIKGRPKVST KVATGNVQNT VEQANDYGVG EEFNYLVGNL
SDYYIP
