ID   VP03_EHV2               Reviewed;        1319 AA.
AC   Q66609;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 80.
DE   RecName: Full=Probable membrane antigen 3;
DE   AltName: Full=Tegument protein;
GN   Name=3;
OS   Equine herpesvirus 2 (strain 86/87) (EHV-2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Percavirus.
OX   NCBI_TaxID=82831;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7783207; DOI=10.1006/jmbi.1995.0314;
RA   Telford E.A.R., Watson M.S., Aird H.C., Perry J., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus 2.";
RL   J. Mol. Biol. 249:520-528(1995).
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000305}.
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DR   EMBL; U20824; AAC13791.1; -; Genomic_DNA.
DR   PIR; S55598; S55598.
DR   RefSeq; NP_042600.1; NC_001650.2.
DR   SMR; Q66609; -.
DR   PRIDE; Q66609; -.
DR   GeneID; 1461051; -.
DR   KEGG; vg:1461051; -.
DR   Proteomes; UP000007083; Genome.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.1330.10; -; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   Gene3D; 3.90.650.10; -; 1.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR010918; PurM-like_C_dom.
DR   InterPro; IPR036676; PurM-like_C_sf.
DR   InterPro; IPR036921; PurM-like_N_sf.
DR   InterPro; IPR024346; Tegument_herpes_virus_N.
DR   Pfam; PF02769; AIRS_C; 1.
DR   Pfam; PF12818; Tegument_dsDNA; 1.
DR   SUPFAM; SSF52317; SSF52317; 1.
DR   SUPFAM; SSF55326; SSF55326; 1.
DR   SUPFAM; SSF56042; SSF56042; 1.
PE   4: Predicted;
KW   Reference proteome; Virion; Virion tegument.
FT   CHAIN           1..1319
FT                   /note="Probable membrane antigen 3"
FT                   /id="PRO_0000406171"
SQ   SEQUENCE   1319 AA;  141568 MW;  E2274B077CB5E12D CRC64;
     MDSTSKRSSF KRARGGRATV YFYVPTWQHG PGGQPPVSSF AFSLVNEVGF GVLFDYGCAG
     TGGATAGRAA AAVDPGVASE AFMEILRTVL PGHRVGAVSE LPAGLGSYLT SGDDGAGGPC
     TLSRDVAPMM QALLEHLIRG QQQLRRPLVG DAGEGAGRGP GEGEATTPIP KILAVSFFHT
     LWSLHSIKQH HAYMLCNQLS SPASFCRTPG YLGFTPLGDP GERPDLKFAR VPVPALAHPK
     ADALAKLPEM FREHDSDVLT GTHRGAIKIR NPFNGLLGYL CRLYAPTSRV FIDRDVFSSN
     GKPDYFGVVY QVGGISTGAS ELDLLYSEAG TFGWGNVLGL HLGVVGSGED PFALQEYLES
     HMLAQRCSGA PTLLGFVRVM DGSAAPPGMG PASRPHSFTG ATRASIISPK ACLSPVRGGG
     ASVFMLGDFF QRPQRAGGAY ASHDSGRRLA SILAAVQTFI NVAGGRAVLS TCQSRLEGTM
     HAKIAAACGV MGLKTYTSLL PEEAVSELSH FSPGNASMNR SILLSKFLNV EAQVVLLTVV
     NTPRNRQILE GVFKTFGCRV SLLGHLARAK KIVLYDDRSP DYCQGGPRYL CFKMHKPRYA
     LPIDRWCGTA SYRPTAPSRV PYNSSDAGPP SDAREVLLGI LRHPTVGCKN YIVKHVDRCA
     SGRVAQQCGV GPLDLPVADY SMVVVEPSAG PPSSMEPWTW ETPQVPDDCF LIHEDGVSGV
     CSALGEKNSV FPFYPEAGAK MAIAESVLSL ALAPIARIED VTVNLSLAWP HLKGAQGEVF
     TLLTRCKRFC EDAGVSCNVT SCASSRRAGG GDPPEGGADI KSFVASAFAY TPCAFWKLTP
     DLKEARSVIL FLPASPGKHA FASVYQQVRG QKKYTGSPVN ISGAYLGKLA RAVLHLRAKR
     LAVSGHDVGD GGLWAALAEM AMAGMRSLDV EVPVRLDGDP MGFLTSETPG VALEVPLSSA
     SAAVEYLRSK YILCYRVGVT GHKTCERMFR ITRGDQVLLE CEQEEVGEAW RSHSVRMERY
     GPCFNRHAYG EGPYEREREA FLAYTPFRIL NRPNKKHRVA VLLLPGCPYP LAALDALRDS
     GFDALAVSHL DLAHVLTDEV CGLFVAGVDN TSDTKTSDAL TSALVHSRNP GVIRDFLSRK
     DTFSLGVGSM ACRILFDGDM AVSPALQSRD IRCVPAVSCK FESRWLNVFI NQSTPAVAFR
     TLRGSLLPCW AQGTHLGFGA PSPECLDRLV ASGQAASMFY GSDVASGPAM AYPANPTETL
     PVAGICSRDG RHLVLLHDIT ASYYLWQWPH VPKSNIPIAV SPWKQVFYDL HAWVTAHSH