VP11_BPPRD
ID VP11_BPPRD Reviewed; 207 AA.
AC P27382; Q3T4M3;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 29-SEP-2021, entry version 75.
DE RecName: Full=Infectivity protein P11;
GN Name=XI;
OS Enterobacteria phage PRD1 (Bacteriophage PRD1).
OC Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC Kalamavirales; Tectiviridae; Alphatectivirus.
OX NCBI_TaxID=10658;
OH NCBI_TaxID=471; Acinetobacter calcoaceticus.
OH NCBI_TaxID=562; Escherichia coli.
OH NCBI_TaxID=584; Proteus mirabilis.
OH NCBI_TaxID=287; Pseudomonas aeruginosa.
OH NCBI_TaxID=294; Pseudomonas fluorescens.
OH NCBI_TaxID=303; Pseudomonas putida (Arthrobacter siderocapsulatus).
OH NCBI_TaxID=90371; Salmonella typhimurium.
OH NCBI_TaxID=666; Vibrio cholerae.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RX PubMed=1853567; DOI=10.1016/0042-6822(91)90995-n;
RA Bamford J.K.H., Haenninen A.-L., Pakula T.M., Ojala P.M., Kalkkinen N.,
RA Frilander M., Bamford D.H.;
RT "Genome organization of membrane-containing bacteriophage PRD1.";
RL Virology 183:658-676(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SEQUENCE REVISION.
RX PubMed=15946683; DOI=10.1016/j.jmb.2005.04.059;
RA Saren A.M., Ravantti J.J., Benson S.D., Burnett R.M., Paulin L.,
RA Bamford D.H., Bamford J.K.H.;
RT "A snapshot of viral evolution from genome analysis of the tectiviridae
RT family.";
RL J. Mol. Biol. 350:427-440(2005).
RN [3]
RP FUNCTION.
RX PubMed=12453208; DOI=10.1046/j.1365-2958.2002.03250.x;
RA Grahn A.M., Daugelavicius R., Bamford D.H.;
RT "Sequential model of phage PRD1 DNA delivery: active involvement of the
RT viral membrane.";
RL Mol. Microbiol. 46:1199-1209(2002).
CC -!- FUNCTION: Component of the phage ejection machinery. Pilot protein for
CC the formation of the tube that conducts the genome into the target
CC cell. Probably involved in penetration of the bacterial outer membrane
CC and for making the peptidoglycan layer accessible to the viral
CC transglycosylase. Essential for viral infectivity.
CC {ECO:0000269|PubMed:12453208}.
CC -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305}; Single-pass
CC membrane protein {ECO:0000305}. Note=Part of the capsid inner membrane.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY848689; AAX45905.1; -; Genomic_DNA.
DR PIR; I36776; WMBPXB.
DR RefSeq; NP_040698.2; NC_001421.2.
DR TCDB; 1.K.2.1.1; the prd1 phage dna delivery (prd1-dd) family.
DR Proteomes; UP000002143; Genome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0039641; C:viral inner membrane; IEA:UniProtKB-KW.
DR GO; GO:0055036; C:virion membrane; IDA:CACAO.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Capsid inner membrane protein; Coiled coil; Direct protein sequencing;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Viral genome ejection through host cell envelope;
KW Viral penetration into host cytoplasm; Virion; Virus entry into host cell.
FT CHAIN 1..207
FT /note="Infectivity protein P11"
FT /id="PRO_0000165353"
FT TRANSMEM 13..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT COILED 64..95
FT /evidence="ECO:0000255"
SQ SEQUENCE 207 AA; 22209 MW; D910C1BC0BF5B0D1 CRC64;
MEKVKAWLIK YKWWIVAAIG GLAAFLLLKN RGGGSGGGGE YMVGSGPVYQ QAGSGAVDNT
MALAALQANT QLSAQNAQLQ AQMDASRLQL ETQLNIETLA ADNAHYSTQS QLQLGMAQVD
LSKYLGDLQS TTSTALAGMQ SDTAKYQSNI QLQAENIRAN TSLAEIDAQK YIVGKQADIA
KYQAKTERRG QDYGFALGLL NFGGKFF
