VP18_BPPRD
ID VP18_BPPRD Reviewed; 90 AA.
AC P27389; Q3T4M8;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 23-FEB-2022, entry version 77.
DE RecName: Full=Protein P18;
DE AltName: Full=GpM;
DE AltName: Full=Protein M;
GN Name=XVIII; Synonyms=M;
OS Enterobacteria phage PRD1 (Bacteriophage PRD1).
OC Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC Kalamavirales; Tectiviridae; Alphatectivirus.
OX NCBI_TaxID=10658;
OH NCBI_TaxID=471; Acinetobacter calcoaceticus.
OH NCBI_TaxID=562; Escherichia coli.
OH NCBI_TaxID=584; Proteus mirabilis.
OH NCBI_TaxID=287; Pseudomonas aeruginosa.
OH NCBI_TaxID=294; Pseudomonas fluorescens.
OH NCBI_TaxID=303; Pseudomonas putida (Arthrobacter siderocapsulatus).
OH NCBI_TaxID=90371; Salmonella typhimurium.
OH NCBI_TaxID=666; Vibrio cholerae.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1853567; DOI=10.1016/0042-6822(91)90995-n;
RA Bamford J.K.H., Haenninen A.-L., Pakula T.M., Ojala P.M., Kalkkinen N.,
RA Frilander M., Bamford D.H.;
RT "Genome organization of membrane-containing bacteriophage PRD1.";
RL Virology 183:658-676(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=15946683; DOI=10.1016/j.jmb.2005.04.059;
RA Saren A.M., Ravantti J.J., Benson S.D., Burnett R.M., Paulin L.,
RA Bamford D.H., Bamford J.K.H.;
RT "A snapshot of viral evolution from genome analysis of the tectiviridae
RT family.";
RL J. Mol. Biol. 350:427-440(2005).
RN [3]
RP FUNCTION.
RX PubMed=12453208; DOI=10.1046/j.1365-2958.2002.03250.x;
RA Grahn A.M., Daugelavicius R., Bamford D.H.;
RT "Sequential model of phage PRD1 DNA delivery: active involvement of the
RT viral membrane.";
RL Mol. Microbiol. 46:1199-1209(2002).
CC -!- FUNCTION: Component of the phage injection machinery. Required for DNA
CC injection in the membrane transformation event. Involved in the
CC formation of the membrane tail tube to connect the virus interior with
CC the host cytosol. Essential for viral infectivity.
CC {ECO:0000269|PubMed:12453208}.
CC -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}. Note=Part of the capsid inner membrane.
CC {ECO:0000305}.
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DR EMBL; AY848689; AAX45911.1; -; Genomic_DNA.
DR PIR; F36776; WMBPMB.
DR RefSeq; NP_040695.1; NC_001421.2.
DR TCDB; 1.K.2.1.1; the prd1 phage dna delivery (prd1-dd) family.
DR Proteomes; UP000002143; Genome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0039641; C:viral inner membrane; IEA:UniProtKB-KW.
DR GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
PE 4: Predicted;
KW Capsid inner membrane protein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Viral genome ejection through host cell envelope;
KW Viral penetration into host cytoplasm; Virion; Virus entry into host cell.
FT CHAIN 1..90
FT /note="Protein P18"
FT /id="PRO_0000165360"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 90 AA; 9789 MW; 0CE80254B79683E4 CRC64;
MPFGLIVIGI ILAIAAYRDT LGELFSIIKD VSKDAKGFGY WVLAAVILGF AASIKPIKEP
VNAFMILLMI VLLIRKRGAI DQISNQLRGS
