ID   VP19_HHV1K              Reviewed;           6 AA.
AC   P23210;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   02-DEC-2020, entry version 44.
DE   RecName: Full=Triplex capsid protein VP19C;
DE   AltName: Full=Virion protein UL38;
DE   Flags: Fragment;
GN   Name=UL38;
OS   Human herpesvirus 1 (strain KOS) (HHV-1) (Human herpes simplex virus 1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Simplexvirus.
OX   NCBI_TaxID=10306;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1846198; DOI=10.1128/jvi.65.2.769-786.1991;
RA   Flanagan W.M., Papavassiliou A.G., Rice M., Hecht L.B., Silverstein S.,
RA   Wagner E.K.;
RT   "Analysis of the herpes simplex virus type 1 promoter controlling the
RT   expression of UL38, a true late gene involved in capsid assembly.";
RL   J. Virol. 65:769-786(1991).
CC   -!- FUNCTION: Structural component of the T=16 icosahedral capsid. The
CC       capsid is composed of pentamers and hexamers of VP5, which are linked
CC       together by heterotrimers called triplex. These triplex are formed by a
CC       single molecule of VP19C and two copies of VP23 which bridge major
CC       capsid protein VP5 multimers together. Triplexes occupy the local
CC       threeflod positions between capsid hexamers and pentamers (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with VP23, VP5 and UL25. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion. Host nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae VP19C family. {ECO:0000305}.
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DR   EMBL; M57646; AAA45830.1; -; Genomic_DNA.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Capsid protein; Host nucleus; Virion.
FT   CHAIN           1..>6
FT                   /note="Triplex capsid protein VP19C"
FT                   /id="PRO_0000115714"
FT   NON_TER         6
SQ   SEQUENCE   6 AA;  703 MW;  67376451A336F000 CRC64;
     MKTNPL