ID   VP22_HCMVA              Reviewed;         358 AA.
AC   P16760; Q7M6Q9;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   19-FEB-2014, sequence version 3.
DT   02-JUN-2021, entry version 69.
DE   RecName: Full=Protein UL24;
GN   Name=UL24;
OS   Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX   NCBI_TaxID=10360;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2161319; DOI=10.1007/978-3-642-74980-3_6;
RA   Chee M.S., Bankier A.T., Beck S., Bohni R., Brown C.M., Cerny R.,
RA   Horsnell T., Hutchison C.A. III, Kouzarides T., Martignetti J.A.,
RA   Preddie E., Satchwell S.C., Tomlinson P., Weston K.M., Barrell B.G.;
RT   "Analysis of the protein-coding content of the sequence of human
RT   cytomegalovirus strain AD169.";
RL   Curr. Top. Microbiol. Immunol. 154:125-169(1990).
RN   [2]
RP   GENOME REANNOTATION.
RX   PubMed=12533697; DOI=10.1099/vir.0.18606-0;
RA   Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J.,
RA   McGeoch D.J., Hayward G.S.;
RT   "The human cytomegalovirus genome revisited: comparison with the chimpanzee
RT   cytomegalovirus genome.";
RL   J. Gen. Virol. 84:17-28(2003).
RN   [3]
RP   ERRATUM OF PUBMED:12533697.
RA   Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J.,
RA   McGeoch D.J., Hayward G.S.;
RL   J. Gen. Virol. 84:1053-1053(2003).
RN   [4]
RP   IDENTIFICATION.
RX   PubMed=15452216; DOI=10.1128/jvi.78.20.10960-10966.2004;
RA   Varnum S.M., Streblow D.N., Monroe M.E., Smith P., Auberry K.J.,
RA   Pasa-Tolic L., Wang D., Camp D.G. II, Rodland K., Wiley S., Britt W.,
RA   Shenk T., Smith R.D., Nelson J.A.;
RT   "Identification of proteins in human cytomegalovirus (HCMV) particles: the
RT   HCMV proteome.";
RL   J. Virol. 78:10960-10966(2004).
RN   [5]
RP   ERRATUM OF PUBMED:15452216.
RA   Varnum S.M., Streblow D.N., Monroe M.E., Smith P., Auberry K.J.,
RA   Pasa-Tolic L., Wang D., Camp D.G. II, Rodland K., Wiley S., Britt W.,
RA   Shenk T., Smith R.D., Nelson J.A.;
RL   J. Virol. 78:13395-13395(2004).
RN   [6]
RP   SUBCELLULAR LOCATION.
RX   PubMed=12029146; DOI=10.1099/0022-1317-83-6-1315;
RA   Adair R., Douglas E.R., Maclean J.B., Graham S.Y., Aitken J.D.,
RA   Jamieson F.E., Dargan D.J.;
RT   "The products of human cytomegalovirus genes UL23, UL24, UL43 and US22 are
RT   tegument components.";
RL   J. Gen. Virol. 83:1315-1324(2002).
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000269|PubMed:12029146}.
CC   -!- SIMILARITY: Belongs to the herpesviridae US22 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=DAA00128.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; X17403; CAA35423.1; -; Genomic_DNA.
DR   EMBL; BK000394; DAA00128.1; ALT_INIT; Genomic_DNA.
DR   PIR; S09787; QQBET1.
DR   RefSeq; YP_081483.2; NC_006273.2.
DR   PRIDE; P16760; -.
DR   DNASU; 3077489; -.
DR   GeneID; 3077489; -.
DR   KEGG; vg:3077489; -.
DR   Proteomes; UP000008991; Genome.
DR   Proteomes; UP000008992; Genome.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   InterPro; IPR003360; US22-like.
DR   Pfam; PF02393; US22; 2.
PE   3: Inferred from homology;
KW   Reference proteome; Virion; Virion tegument.
FT   CHAIN           1..358
FT                   /note="Protein UL24"
FT                   /id="PRO_0000116307"
SQ   SEQUENCE   358 AA;  40186 MW;  A0184BE082937DAE CRC64;
     MEETRAGRYI VRAGSGGQTE DTASGAESVL ATLAAVRTRR RSVVCDGPPG SPTDSARHMS
     DLASLALTAE FGLGCLEAYV RINAGQVLPV VWPPGWNLVL QEIETDEDFK PEDVKAWSHY
     LCCQTRLAFV GRFVNEGVLS PDQQKKTAVC LISDEGYVFC YVREDTAVYY LARNLMEFAR
     VGLRAVETLH CMRYLTSSLV KRYFRPLLRA WSLGLDTMAR FIIRHHGQFM PLTYPPGTEL
     RLCNLRCFEN SVEGGHLLRN IKTAFGMRVL GLGTVSLKGE NAPFPHLRWP VDLIPIVVAY
     TGAVYACDVR DDRYIRVGDN LNTFMCLGLN LLFENRRFSG HNGIYDRVPD CPKGRQHR