VP2_FCVUR
ID VP2_FCVUR Reviewed; 106 AA.
AC Q66916;
DT 09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 29-SEP-2021, entry version 61.
DE RecName: Full=Protein VP2;
DE AltName: Full=Minor capsid protein;
GN ORFNames=ORF3;
OS Feline calicivirus (strain Cat/United States/Urbana/1960) (FCV).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Caliciviridae; Vesivirus.
OX NCBI_TaxID=292349;
OH NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=7618275; DOI=10.1006/viro.1995.1354;
RA Sosnovtsev S.V., Green K.Y.;
RT "RNA transcripts derived from a cloned full-length copy of the feline
RT calicivirus genome do not require VpG for infectivity.";
RL Virology 210:383-390(1995).
RN [2]
RP PROTEIN SEQUENCE OF 1-20 AND 102-106, AND IDENTIFICATION.
RX PubMed=11062050; DOI=10.1006/viro.2000.0579;
RA Sosnovtsev S.V., Green K.Y.;
RT "Identification and genomic mapping of the ORF3 and VPg proteins in feline
RT calicivirus virions.";
RL Virology 277:193-203(2000).
RN [3]
RP FUNCTION.
RX PubMed=15767403; DOI=10.1128/jvi.79.7.4012-4024.2005;
RA Sosnovtsev S.V., Belliot G., Chang K.O., Onwudiwe O., Green K.Y.;
RT "Feline calicivirus VP2 is essential for the production of infectious
RT virions.";
RL J. Virol. 79:4012-4024(2005).
RN [4]
RP INTERACTION WITH CAPSID PROTEIN.
RX PubMed=16432023; DOI=10.1099/vir.0.81456-0;
RA Kaiser W.J., Chaudhry Y., Sosnovtsev S.V., Goodfellow I.G.;
RT "Analysis of protein-protein interactions in the feline calicivirus
RT replication complex.";
RL J. Gen. Virol. 87:363-368(2006).
CC -!- FUNCTION: Minor structural protein present in one or two copies per
CC virion. Does not seem to play a role in capsid assembly, but is
CC essential for production of infectious virus.
CC {ECO:0000269|PubMed:15767403}.
CC -!- SUBUNIT: May interact with capsid protein.
CC -!- SUBCELLULAR LOCATION: Virion. Host cytoplasm.
CC -!- MISCELLANEOUS: Translated by a ribosomal termination-reinitiation
CC process from the bicistronic mRNA coding for VP1 and VP2.
CC -!- SIMILARITY: Belongs to the vesivirus VP2 protein family. {ECO:0000305}.
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DR EMBL; L40021; AAA79325.1; -; Genomic_RNA.
DR RefSeq; NP_783198.1; NC_001481.2.
DR SMR; Q66916; -.
DR GeneID; 1502253; -.
DR KEGG; vg:1502253; -.
DR Proteomes; UP000001098; Genome.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR007996; Vesivirus_VP2.
DR Pfam; PF05332; DUF743; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Host cytoplasm; Reference proteome; Virion.
FT CHAIN 1..106
FT /note="Protein VP2"
FT /id="PRO_0000100125"
SQ SEQUENCE 106 AA; 12199 MW; DCD55D2DE1967F13 CRC64;
MNSILGLIDT VTNTIGKAQQ IELDKAALGQ QRELALQRMN LDRQALNNQV EQFNKILEQR
VQGPLQSVRL ARAAGFRVDP YSYTNQNFYD DQLNAIRLSY RNLFKN