VP2_LORDV
ID VP2_LORDV Reviewed; 268 AA.
AC P54636;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 23-FEB-2022, entry version 47.
DE RecName: Full=Protein VP2;
DE AltName: Full=Minor capsid protein;
GN ORFNames=ORF3;
OS Lordsdale virus (strain GII/Human/United Kingdom/Lordsdale/1993) (Human
OS enteric calicivirus) (Hu/NV/LD/1993/UK).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Caliciviridae; Norovirus.
OX NCBI_TaxID=82658;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=7561776; DOI=10.1099/0022-1317-76-9-2349;
RA Dingle K.E., Lambden P.R., Caul E.O., Clarke I.N.;
RT "Human enteric Caliciviridae: the complete genome sequence and expression
RT of virus-like particles from a genetic group II small round structured
RT virus.";
RL J. Gen. Virol. 76:2349-2355(1995).
CC -!- FUNCTION: Minor structural protein present in one or two copies per
CC virion. Stabilizes capsid protein VP1 by protecting it from disassembly
CC and degradation. May play a role in RNA genome packaging (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion. Host cytoplasm {ECO:0000250}.
CC -!- MISCELLANEOUS: Translated by a ribosomal termination-reinitiation
CC process from the bicistronic mRNA coding for VP1 and VP2.
CC -!- SIMILARITY: Belongs to the norovirus VP2 family. {ECO:0000305}.
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DR EMBL; X86557; CAA60256.1; -; Genomic_RNA.
DR PRIDE; P54636; -.
DR Proteomes; UP000007767; Genome.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR004278; RNA_pol/capsid.
DR Pfam; PF03035; RNA_capsid; 1.
PE 3: Inferred from homology;
KW Host cytoplasm; Virion.
FT CHAIN 1..268
FT /note="Protein VP2"
FT /id="PRO_0000100130"
FT REGION 132..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 268 AA; 28458 MW; FE6F19E4D7D1587E CRC64;
MAGAFFAGLA SDVLGSGLGS LINAGAGAIN QKVEFENNRK LQQASFQFSS TLQQASFQHD
KEMLQAQIEA TQKLQQDLMK VKQAVLLEGG FSTADAARGA INAPMTKALD WSGTRYWAPD
ARVTTYNAGH FSTPQSLGAL TGRTNSRVSA PARSSPSALS NAPTATSLHS NQTVSTRLGS
SAGSGTGVSS LSSAARTRSW VEDQNRNLSP FMRGALNTSF VTPPSSRSSS QSTVSTVPKE
ILDSWTGAFN TRRQPLFAHI RKRGESRV