ID   VP2_SOUV3               Reviewed;         211 AA.
AC   Q04550;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   23-FEB-2022, entry version 49.
DE   RecName: Full=Protein VP2;
DE   AltName: Full=Minor capsid protein;
GN   ORFNames=ORF3;
OS   Southampton virus (strain GI/Human/United Kingdom/Southampton/1991) (SHV)
OS   (Hu/NV/SHV/1991/UK).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Picornavirales; Caliciviridae; Norovirus.
OX   NCBI_TaxID=37129;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8380940; DOI=10.1126/science.8380940;
RA   Lambden P.R., Caul E.O., Ashley C.R., Clarke I.N.;
RT   "Sequence and genome organization of a human small round-structured
RT   (Norwalk-like) virus.";
RL   Science 259:516-519(1993).
CC   -!- FUNCTION: Minor structural protein present in one or two copies per
CC       virion. Stabilizes capsid protein VP1 by protecting it from disassembly
CC       and degradation. May play a role in RNA genome packaging (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion. Host cytoplasm {ECO:0000250}.
CC   -!- MISCELLANEOUS: Translated by a ribosomal termination-reinitiation
CC       process from the bicistronic mRNA coding for VP1 and VP2.
CC   -!- SIMILARITY: Belongs to the norovirus VP2 family. {ECO:0000305}.
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DR   EMBL; L07418; AAA92985.1; -; Genomic_RNA.
DR   PIR; C37491; C37491.
DR   Proteomes; UP000007226; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004278; RNA_pol/capsid.
DR   Pfam; PF03035; RNA_capsid; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Virion.
FT   CHAIN           1..211
FT                   /note="Protein VP2"
FT                   /id="PRO_0000100131"
SQ   SEQUENCE   211 AA;  22257 MW;  3D6D1B51CC3C27B4 CRC64;
     MAQAIIGAIA ASAAGSALGA GIQAGAEAAL QSQRYQQDLA LQRNTFEHDK DMLSYQVQAS
     NALLAKNLNT RYSMLIAGGL SSADASRAVA GAPVTRLIDW NGTRVAAPRS SATTLRSGGF
     MAVPMPVQPK SKTPQSSGFS NPAYDMSTVS SRTSSWVQSQ NSLRSVSPFH RQALQTVWVT
     PPGSTSSSSV SSTPYGVFNT DRMPLFANLR R