VP302_LYCMC
ID VP302_LYCMC Reviewed; 93 AA.
AC P0CJ14;
DT 11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2011, sequence version 1.
DT 25-MAY-2022, entry version 16.
DE RecName: Full=Venom protein 302;
DE Flags: Precursor;
OS Lychas mucronatus (Chinese swimming scorpion).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC Scorpiones; Buthida; Buthoidea; Buthidae; Lychas.
OX NCBI_TaxID=172552;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Yunnan; TISSUE=Venom gland;
RX PubMed=20663230; DOI=10.1186/1471-2164-11-452;
RA Zhao R., Ma Y., He Y., Di Z., Wu Y.-L., Cao Z.-J., Li W.-X.;
RT "Comparative venom gland transcriptome analysis of the scorpion Lychas
RT mucronatus reveals intraspecific toxic gene diversity and new venomous
RT components.";
RL BMC Genomics 11:452-452(2010).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GT029300; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; P0CJ14; -.
DR SMR; P0CJ14; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.
DR GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR000867; IGFBP-like.
DR InterPro; IPR011390; IGFBP_rP_mac25.
DR PANTHER; PTHR14186; PTHR14186; 1.
DR Pfam; PF00219; IGFBP; 1.
DR SMART; SM00121; IB; 1.
DR SUPFAM; SSF57184; SSF57184; 1.
DR PROSITE; PS51323; IGFBP_N_2; 1.
PE 2: Evidence at transcript level;
KW Secreted; Signal.
FT SIGNAL 1..16
FT /evidence="ECO:0000255"
FT CHAIN 17..93
FT /note="Venom protein 302"
FT /id="PRO_0000403906"
FT DOMAIN 17..93
FT /note="IGFBP N-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00653"
SQ SEQUENCE 93 AA; 9988 MW; 54951605AF8B525F CRC64;
MLKLVILLCV IESIYSLSCP CQWNKSLRDS CRIPENCLAG TTKDVCGCCD VCAKIEGESC
GGPWNIGGSC AVGLTCVKVD KRNFHSKGVC KLN