ID   VP3_AHSV6               Reviewed;         905 AA.
AC   O71025;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Core protein VP3;
GN   Name=Segment-3; Synonyms=L3;
OS   African horse sickness virus 6 (AHSV-6).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=86060;
OH   NCBI_TaxID=9838; Camelus dromedarius (Dromedary) (Arabian camel).
OH   NCBI_TaxID=9615; Canis lupus familiaris (Dog) (Canis familiaris).
OH   NCBI_TaxID=9793; Equus asinus (Donkey) (Equus africanus asinus).
OH   NCBI_TaxID=9796; Equus caballus (Horse).
OH   NCBI_TaxID=9794; Equus hemionus (Onager) (Asian wild ass).
OH   NCBI_TaxID=89252; Equus quagga burchellii (Plains zebra) (Equus burchelli).
OH   NCBI_TaxID=9785; Loxodonta africana (African elephant).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=9617769; DOI=10.1016/s0168-1702(97)00131-7;
RA   Williams C.F., Inoue T., Lucus A.-M., Zanotto P., Roy P.;
RT   "The complete sequence of four major structural proteins of African horse
RT   sickness virus serotype 6: evolutionary relationships within and between
RT   the orbiviruses.";
RL   Virus Res. 53:53-73(1998).
CC   -!- FUNCTION: The VP3 protein is one of the five proteins (with VP1, VP4,
CC       VP6 and VP7) which form the inner capsid of the virus.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the orbivirus VP3 family. {ECO:0000305}.
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DR   EMBL; AF021236; AAC40995.1; -; mRNA.
DR   SMR; O71025; -.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR002614; Inner_layer_core_VP3_Orbivir.
DR   InterPro; IPR016029; Inner_layer_core_VP3_Reovir.
DR   Pfam; PF01700; Orbi_VP3; 1.
DR   SUPFAM; SSF56831; SSF56831; 1.
PE   2: Evidence at transcript level;
KW   Virion.
FT   CHAIN           1..905
FT                   /note="Core protein VP3"
FT                   /id="PRO_0000222700"
SQ   SEQUENCE   905 AA;  103306 MW;  8748565C70D9B90C CRC64;
     MQGNERIQDK NEKEKAYAPY LDGASVSTDN GPILSVFALQ EIMQKIRQNQ SDMAAHAPDV
     DGAIPEVMTI ISGIKGLLEE KDYKVINAPP NSFRTIPMQS MEYVLQVNTF YERMSEIGGP
     VDETDPIGFY ALILEKLKFL KSEGAFILQG IATKDYRGAE IADPEIIGVS FQNALSHLAA
     IDRQIIQDTL NGMIIENGLV ADRNVDVFRA AMSDPIYRIR NVLQGYIEGI QYGELRESVN
     WLMRLGLRKR IEFANDFLTD FRRADTIWII SQRLPINANV IWNVPRCHIA NLNTNVALCL
     PTGEYLMPNP RINSITITQR ITQTNPFSII SGLTPTAVQM NDVRKIYLAL MFPNQIILDI
     KPDSSHAVDP VLRMVAGVLG HVMFTYGPIM TNITPTMAEL LDAALSDYLL YMYNNRIPIN
     YGPTGQPLDF RIGARNQYDC NAFRADPQTG RGYNGWGVVD VQRVQPSPYD HVQRVIRYCD
     IDSREIIDPR TYGMNMTYPI FREMLRMLVA AGKDQEAAYL RQMLPFHMIR FARINQIINE
     DLLSAFSLPD QNFDVVLHNL IQGNFGETDP VILEVSWASI WFAFVRRFEP IARSDLLEAA
     PLIEARYAAE LSTMQMDVQQ LRMMRARVPD TVINATPSQC WKAVLKNAPE PIKNLMNLSH
     SFSFVNVRDI VRWSQQRDIQ ESLAYVLNRE AWAIANDFED LMLVDHVYIQ RTMLPEPRLD
     DINEFRRQGF FHTNMIDGAP PIGDVTHYTY AIANLQANMG QFRAAIRRTL DDNGWIQFGG
     MLRNIKIKFF DSRPPDEILT AMPYVYTEEE RDGVRMVAFK YATTATAYFL LYNVEYSNTP
     DTLITVNPTF TMTKIHMRKK IVRRVRAPDV LSQVNKRLVA YKGKMRLMDV TKCLKTGVQL
     ARPTI