ID   VP3_BTV10               Reviewed;         901 AA.
AC   P12435;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   23-FEB-2022, entry version 73.
DE   RecName: Full=Core protein VP3;
DE   AltName: Full=Major inner capsid protein;
GN   Name=Segment-3; Synonyms=L3;
OS   Bluetongue virus 10 (isolate USA) (BTV 10).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=10900;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2998117; DOI=10.1016/0168-1702(85)90007-3;
RA   Ghiasi H., Purdy M.A., Roy P.;
RT   "The complete sequence of bluetongue virus serotype 10 segment 3 and its
RT   predicted VP3 polypeptide compared with those of BTV serotype 17.";
RL   Virus Res. 3:181-190(1985).
CC   -!- FUNCTION: The VP3 protein is one of the five proteins (with VP1, VP4,
CC       VP6 and VP7) which form the inner capsid of the virus.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the orbivirus VP3 family. {ECO:0000305}.
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DR   EMBL; M22096; AAA42832.1; -; Genomic_RNA.
DR   PIR; S07419; S07419.
DR   RefSeq; YP_052959.1; NC_006014.1.
DR   SMR; P12435; -.
DR   GeneID; 2943153; -.
DR   KEGG; vg:2943153; -.
DR   Proteomes; UP000007662; Genome.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR002614; Inner_layer_core_VP3_Orbivir.
DR   InterPro; IPR016029; Inner_layer_core_VP3_Reovir.
DR   Pfam; PF01700; Orbi_VP3; 1.
DR   SUPFAM; SSF56831; SSF56831; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Virion.
FT   CHAIN           1..901
FT                   /note="Core protein VP3"
FT                   /id="PRO_0000222695"
SQ   SEQUENCE   901 AA;  103343 MW;  4E485F5A38FC6456 CRC64;
     MAAQNEQRPE RIKTTPYLEG DVLSSDSGPL LSVFALQEIM QKVRQVQADY MTATREVDFT
     VPDVQKILDD IKTLAAEQVY KIVKVPSISF RHIVMQSRDR VLRVDTYYEE MSQVGDVITE
     DEPEKFYSTI IKKVRFIRGK GSFILHDIPT RDHRGMEVAE PEVLGVEFKN VLPVLTAEHR
     AMIQNALDGS IIENGNVATR DVDVFIGACS EPIYRIYNRL QGYIEAVQLQ ELRNSIGWLE
     RLGQRKRITY SQEVLTDFRR QDTIWVLALQ LPVNPQVVWD VPRSSIANLI MNIATCLPTG
     EYIAPNPRIS SITLTQRITT TGPFAILTGS TPTAQQLNDV RKIYLALMFP GQIVLDLKID
     PGERMDPAVR MVAGVVGHLL FTAGGRFTNL TQNMARQLDI ALNDYLLYMY NTRVQVNYGP
     TGEPLDFQIG RNQYDCNVFR ADFATGTGYN GWATIDVEYR DPAPYVHAQR YIRYCGIDSR
     ELINPTTYGI GMTYHCYNEM LRMLVAAGRD SEAAYFRSML PFHMVRFARI NQIINEDLHS
     VFSLPDDMFN ALLPDLIAGA HQNADPVVLD VSWISLWFAF NRSFEPTHRN EMLEIAPLIE
     SVYASELSVM KVDMRHLSLM QRRFPDVLIQ ARPSHFWKAV LNDSPEAVKA VMNLSHSHNF
     INIRDMMRWV LLPSLQPSLK LVLEEEAWAA ANDFEDLMLT DQVYMHRDML PEPRLDDIER
     FRQEGFYYTN MLEAPPEIDR VVQYTYEIAR LQANMGQFRA ALRRIMDDDD WVRFGGVLRT
     VRVKFFDARP PDDILQGLPF SYDTNEKGGL SYATIKYATE TTIFYLIYNV EFSNTPDSLV
     LINPTYTMTK VFINKRIVER VRVGQILAVL NRRFVAYKGK MRIMDITQSL KMGTKLAAPT
     V