ID   VP3_BTV11               Reviewed;         901 AA.
AC   Q65749;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   29-SEP-2021, entry version 59.
DE   RecName: Full=Core protein VP3;
DE   AltName: Full=Major inner capsid protein;
GN   Name=Segment-3; Synonyms=L3;
OS   Bluetongue virus 11 (isolate USA) (BTV 11).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=33716;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8079518; DOI=10.1016/0168-1702(94)90086-8;
RA   Hwang G.-Y., Xiang M., Li J.K.-K.;
RT   "Analyses and conservation of sequences among the cognate L3 segments of
RT   the five United States bluetongue viruses.";
RL   Virus Res. 32:381-389(1994).
CC   -!- FUNCTION: The VP3 protein is one of the five proteins (with VP1, VP4,
CC       VP6 and VP7) which form the inner capsid of the virus.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the orbivirus VP3 family. {ECO:0000305}.
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DR   EMBL; L19968; AAA42846.1; -; Genomic_RNA.
DR   SMR; Q65749; -.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR002614; Inner_layer_core_VP3_Orbivir.
DR   InterPro; IPR016029; Inner_layer_core_VP3_Reovir.
DR   Pfam; PF01700; Orbi_VP3; 1.
DR   SUPFAM; SSF56831; SSF56831; 1.
PE   3: Inferred from homology;
KW   Virion.
FT   CHAIN           1..901
FT                   /note="Core protein VP3"
FT                   /id="PRO_0000222696"
SQ   SEQUENCE   901 AA;  103406 MW;  2C81F5D7CA304D0D CRC64;
     MAAQNEQRSE RIKTTPYLEG DVLSSDSGPL LSVFALQEIM QKVRQVQADY MTATREVDFT
     VPDVQKILDD IKTLAAEQVY KIVKVPNILF RHIVMQSRDR VLRVDTYYEE MSQVGDVITE
     DEPEKFYSTI IKKVRFIRGK GSFILHDIPT RDHRGMEVAE PEVLGVEFKN VLPVLTAEHR
     AMIQNALDGS IIENGNVATR DVDVFIGACS EPIYRIYNRL QGYIEAVQLQ ELRNSIGWLE
     RLGLRKRITY SQEVLTDFRR QDTIWVLALQ LPVNPQVVWD VPRSSIANLI MNIATCLPTG
     EYIAPNPRIS SITLTQRITT TGPFAILTGS TPTAQQLNDV RKIYLALMFP GQIILDLKID
     PGERMDPAVR MVAGVVGHLL FTAGGRFTNL TQNMARQLDI ALNDYLLYMY NTRVQVNYGP
     TGEPLDFQIG RNQYDCNVFR ADFATGTGYN GWATIDVEYR DPAPYVHAQR YIRYCGIDSR
     ELINPTTYGI GMTYHCYNEM LRMLVAAGKD SEAAYFRSML PFHMVRFARI NQIINEDLHS
     VFSLPDDMFN ALLPDLIAGA HQNADPVVLD VSWISLWFAF NRSFEPTHRN EMLEIAPLIE
     SVYASELSVM KVDMRHLSLM QRRFPDVLIQ ARPSHFWKAV LNDSPEAVKA VMNLSHSHNF
     INIRDMMRWV MLPSLQPSLK LVLEEEAWAA ANDFEDLMLT DQVYMHRDML PEPRLDDVER
     FRQEGFYYTN MLEAPPEIDR VVQYTYEIER LQANMGQFRA ALRRIMDDDD WVRFGGVLRT
     VRVKFFDARP PDDILQGLPF SYDTNEKGGL SYATIKYATE TTIFYQIYNA EFSNTPDSLV
     LINPTYTMTK VFINKRIVER VRVGQILAVL NRRFVAYKGK MRIMDITQSL KMGTKLAAPT
     V