ID   VP3_BTV13               Reviewed;         901 AA.
AC   Q65750;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 59.
DE   RecName: Full=Core protein VP3;
DE   AltName: Full=Major inner capsid protein;
GN   Name=Segment-3; Synonyms=L3;
OS   Bluetongue virus 13 (isolate USA) (BTV 13).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=33717;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8079518; DOI=10.1016/0168-1702(94)90086-8;
RA   Hwang G.-Y., Xiang M., Li J.K.-K.;
RT   "Analyses and conservation of sequences among the cognate L3 segments of
RT   the five United States bluetongue viruses.";
RL   Virus Res. 32:381-389(1994).
CC   -!- FUNCTION: The VP3 protein is one of the five proteins (with VP1, VP4,
CC       VP6 and VP7) which form the inner capsid of the virus.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the orbivirus VP3 family. {ECO:0000305}.
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DR   EMBL; L19969; AAA42847.1; -; Genomic_RNA.
DR   SMR; Q65750; -.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR002614; Inner_layer_core_VP3_Orbivir.
DR   InterPro; IPR016029; Inner_layer_core_VP3_Reovir.
DR   Pfam; PF01700; Orbi_VP3; 1.
DR   SUPFAM; SSF56831; SSF56831; 1.
PE   3: Inferred from homology;
KW   Virion.
FT   CHAIN           1..901
FT                   /note="Core protein VP3"
FT                   /id="PRO_0000222697"
SQ   SEQUENCE   901 AA;  103370 MW;  F37AE6AD3AF2A768 CRC64;
     MAAQNEQRPE RIKTTPYLEG DVLSNDSGPL LSVFALQEIM QKVRQVQADY MTATREVDFT
     VPDVQKILDD IKTLAAEQVY KIVKIPSISF RHIVMQSRDR VLRVDTYYEE MSQVGDVITE
     DEPEKFYSTI IKKVRFIREK GSFILHDIPT RDHRGMEVAE PEVLGVEFKN VLPVLTAEHR
     AMIQNALDGS IIENGNVATR DVDVFIGACS EPIYRIYNRL QGYIEAVQLQ ELRNSIGWLG
     RLGQRKRITY SQEVLTDFRR QDTIWVLALQ LPVNPQVVWD VPRSSIANLI MNIATCLPTG
     EYIAPNPRIS SITLTQRITT TGPFAILTGS TPTAQQLNDV RKIYLALMFP GQIILDLKID
     PGERMDPAVR MVAGVVGHLL FTAGGRFTNL TQDMARQLDI ALNDYLLYMY NTRVQVKYGP
     TGEPLDFQMG RNQYDCNVFR ADFATGTGYN GWATIDVEYR DPAPYVHAQR YIRYCGIDSR
     ELINPTTYGI GMTYHCYNEM LRMLVAAGKD SEAAYFRSML PFHMVRFARI NQIINEDLHS
     VFSLPDDMFN ALLPDLIAGA HQNADPVVLD VSWISLWFAF NRSFEPTHRN EMLEIAPLIE
     SVYASELSVM KVDMRHLSLM QRRFPDVLIQ ARPSHFWKAV LNDSPEAVKA VMNLSHSHNF
     INIRDMMRWV LLPSLQPSLK LVLEEEAWAA ANDFEDLMLT DQVYMHRDML PEPRLDDIER
     FRQEGFYYTN MLEAPPEIDR VDQNTYEIAR LQANMGQFRA ALRRIMDDDD WVRFGGVLRT
     VRVKFFDARP PDDILQGLPF SYDTNEKGGL SYATIKYATE TTIFYLIYNV EFSNTPDSLV
     LINPTYTMTK VFINKRIVER VRVGQILAVL NRRFVAYKGK MRIMDITQSL KMGTKLAAPT
     V