ID   VP3_BTV17               Reviewed;         901 AA.
AC   P03539;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   29-SEP-2021, entry version 66.
DE   RecName: Full=Core protein VP3;
DE   AltName: Full=Major inner capsid protein;
GN   Name=Segment-3; Synonyms=L3;
OS   Bluetongue virus 17 (isolate USA) (BTV 17).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=33718;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=6206235; DOI=10.1128/jvi.51.3.754-759.1984;
RA   Purdy M.A., Petre J., Roy P.;
RT   "Cloning of the bluetongue virus L3 gene.";
RL   J. Virol. 51:754-759(1984).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2989873;
RA   Roy P., Purdy M.A., Petre J., Rao C.D.;
RT   "Cloning and nucleotide sequencing of bluetongue virus genomes.";
RL   Prog. Clin. Biol. Res. 178:363-370(1985).
CC   -!- FUNCTION: The VP3 protein is one of the five proteins (with VP1, VP4,
CC       VP6 and VP7) which form the inner capsid of the virus.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the orbivirus VP3 family. {ECO:0000305}.
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DR   EMBL; K02369; AAA42831.1; -; Genomic_RNA.
DR   EMBL; M32722; AAA42839.1; -; Genomic_RNA.
DR   PIR; A04148; P3XR17.
DR   SMR; P03539; -.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR002614; Inner_layer_core_VP3_Orbivir.
DR   InterPro; IPR016029; Inner_layer_core_VP3_Reovir.
DR   Pfam; PF01700; Orbi_VP3; 1.
DR   SUPFAM; SSF56831; SSF56831; 1.
PE   3: Inferred from homology;
KW   Virion.
FT   CHAIN           1..901
FT                   /note="Core protein VP3"
FT                   /id="PRO_0000222698"
SQ   SEQUENCE   901 AA;  103415 MW;  C93F110D9C313A3C CRC64;
     MAAQNEQRPE RIKTTPYLEG DVLSSDSGPL LSVFALQEIM QKVRQVQADY MTATREVDFT
     VPDVQKILDD IKTLAAEQVY KIVKVPNISF RHIVMQSRDR VLRVDTYYEE MSQVGDVITE
     DEPEKFYSTI IKKVRFIRGK GSFILHDIPT RDHRGMEVAE PEVLGVEFKN VLPVLTAEHR
     AMIQNALDGS IIENGNVATR DVDVFIGACS EPIYRIYNRL QGYIEAVQLQ ELRNSIGWLE
     RLGQRKRITY SQEVLTDFRR QDTIWVLALQ LPVNPQVVWD VPRSSIANLI MNIATCLPTG
     EYIAPNPRIS SITLTQRITT TGPFAILTGS TPTAQQLNDV RKIYLALMFP GQIILDLKID
     PGERMDPAVR MVAGVVGHLL FTAGGRFTNL TQNMARQLDI ALNDYLLYMY NTRVQVNYGP
     TGEPLDFQIG RNQYDCNVFR ADFATGTGYN GWATIDVEYR DLAPYVHAQR YIRYCGIDSR
     ELINPTTYGI GMTYHCYNEM LRMLVAAGKD SEAAYFRSML PFHMVRFARI NQIINEDLHS
     VFSLPDDMFN ALLPDLIAGA HQNADPVVLD VSWISLWFAF NRSFEPTHRN EMLEIAPLIE
     SVYASELSVM KVDMRHLSLM QRRFPDVLIQ ARPSHFWKAV LNDSPEAVKA VMNLSHSHNF
     INIRDMMRWV MLPSLQPSLK LVLEEEAWAA ANDFEDLMLT DQVYMHRDML PEPRLDDVER
     FRQEGFYYTN MLEAPPEIDR VVQYTYEIAR LQANMGQFRA ALRRIMDDDD WVRFGGVLRT
     VRVKFFDARP PDDILQGLPF SYDTNEKGGL SYATIKYATE TTIFYLIYNV EFSNTPDSLV
     LINPAYTMTK VFINKRIVER VRVRQILAVL NRRFVAYKGK MRIMDITQSL KMGAKLAAPT
     V