ID   VP3_EHDVA               Reviewed;         899 AA.
AC   P33474;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   29-SEP-2021, entry version 61.
DE   RecName: Full=Core protein VP3;
GN   Name=Segment-3; Synonyms=L3;
OS   Epizootic hemorrhagic disease virus 2 (strain Australia) (EHDV-2).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=33719;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9872; Odocoileus hemionus (Mule deer) (Cervus hemionus).
OH   NCBI_TaxID=9874; Odocoileus virginianus (White-tailed deer).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1962502; DOI=10.1016/0168-1702(91)90068-7;
RA   Gould A.R., Pritchard L.I.;
RT   "Phylogenetic analyses of the complete nucleotide sequence of the capsid
RT   protein (VP3) of Australian epizootic haemorrhagic disease of deer virus
RT   (serotype 2) and cognate genes from other orbiviruses.";
RL   Virus Res. 21:1-18(1991).
CC   -!- FUNCTION: The VP3 protein is one of the five proteins (with VP1, VP4,
CC       VP6 and VP7) which form the inner capsid of the virus.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the orbivirus VP3 family. {ECO:0000305}.
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DR   EMBL; S68010; AAB20469.2; -; Genomic_RNA.
DR   PIR; A43969; A43969.
DR   SMR; P33474; -.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR002614; Inner_layer_core_VP3_Orbivir.
DR   InterPro; IPR016029; Inner_layer_core_VP3_Reovir.
DR   Pfam; PF01700; Orbi_VP3; 1.
DR   SUPFAM; SSF56831; SSF56831; 1.
PE   3: Inferred from homology;
KW   Virion.
FT   CHAIN           1..899
FT                   /note="Core protein VP3"
FT                   /id="PRO_0000222702"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   899 AA;  103151 MW;  D7868285DEC8BEF5 CRC64;
     MAEPPDAATP KTSPYLKGDE LSSDSGPLLS IFALQEIMQK VRQAKSEYMA ATKDVDLTIP
     DVQKIIDGVK ELASETIYKV VNKPLISYRH IVMQSRDRFL RVDTYYERMS EVGDKIDENE
     PAKFYETVIK KVRHLRTEGA FVLHNIPTRD HRGMEIADPE ILGVDVKSIL PVLTAEHRAM
     VQHILDGAII ENGIVATRDV DVYFGACSES VYRIYNRLQG YIEAVQLEEL RAAITWLERL
     GRRKRMTFSQ EFLTDFRRAD TIWVLALQLP ANPRVIWQVP RCSIANLIMN IATCLPTGEY
     VSPNPRIASI TLTQRITTTG PFAILTGSTP TAQQLDDVRK IYLALMFPGQ IVLDLKIDPG
     ERMDPAVRMV AGVVGHLMFT AGPRFTNITQ NMARQLDIAL ADFLLYMYNT RIQVQYGPTG
     EPLDFRIGRG QYDCNAFRTN FQTGAGYNGW GLVDVENREP APYDHVQRFI RYCNIDSREL
     IHPATFGIGM NYYCYNEMLR MLVAAGKDTE AAFFRNMLPF HMVRFARINQ IINEDLHSAF
     SMPDDQFNVL LANMIAGAQE RMDPVVLDIS WISIWYAFNR SFEPTRRNEM LESAPLIESV
     YASELTVMKI DMQQMALLQR RFPDVLIEAR PTHFWKAVME VSPEPVRAIM DLAHSHSFIN
     IRDMMRWIGL PSMQPSMKLV LEEEAWAVAN DFEELMLTDQ VYMFRDMLPE PRLDDIERFR
     QEGFYYTNML DGPPTIDRVV QYTYEVARLQ ANMGQLRAAL RRIMDEEGWV RFGGVLRTVR
     VKFFDSRPPE EILQALPFDY QTSEKGGLTY ATIKYANDTT IYYLIYNVEY SNLPDSLVLI
     NPTYVMTKVF INKRIVERVR VGQALAVMNK RFIAYKGKMR IMDITQALKV GTKLAAPTV