ID   VP41_ISOHA              Reviewed;          10 AA.
AC   P0DUU8;
DT   29-SEP-2021, integrated into UniProtKB/Swiss-Prot.
DT   29-SEP-2021, sequence version 1.
DT   23-FEB-2022, entry version 2.
DE   RecName: Full=Venom peptide Sh41 {ECO:0000303|PubMed:34023397};
OS   Isodontia harmandi (Grass-carrying wasp).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Spheciformes; Sphecidae; Sphecinae; Sphecina; Isodontia.
OX   NCBI_TaxID=2838365;
RN   [1]
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, AND MASS SPECTROMETRY.
RC   TISSUE=Venom;
RX   PubMed=34023397; DOI=10.1016/j.peptides.2021.170575;
RA   Nihei K.I., Peigneur S., Tytgat J., Lange A.B., Konno K.;
RT   "Isolation and characterization of FMRFamide-like peptides in the venoms of
RT   solitary sphecid wasps.";
RL   Peptides 142:170575-170575(2021).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:34023397}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000305|PubMed:34023397}.
CC   -!- MASS SPECTROMETRY: Mass=1148.6; Method=MALDI; Note=Monoisotopic mass.;
CC       Evidence={ECO:0000269|PubMed:34023397};
CC   -!- MISCELLANEOUS: Does not show activity on voltage-gated sodium channels,
CC       potassium channels, and calcium channels. All the following channels
CC       have been tested at 10 uM: Kv1.1/KCNA1, Kv1.2/KCNA2, Kv1.3/KCNA3,
CC       Kv1.4/KCNA4, Kv1.5/KCNA5, Kv1.6/KCNA6, Kv2.1/KCNB1, Kv3.1/KCNC1,
CC       Kv4.2/KCND2, Kv4.3/KCND3, Shaker IR, and Kv11.1/KCNH2/ERG1, as well as
CC       Nav1.2/SCN2A, Nav1.4/SCN4A, Nav1.5/SCN5A, Nav1.6/SCN8A, Nav1.8/SCN10A,
CC       and DmNav1, and the nicotinic acetylcholine receptor alpha-7 (CHRNA7).
CC       {ECO:0000269|PubMed:34023397}.
CC   -!- SIMILARITY: Belongs to the SA81-like family. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Secreted.
FT   PEPTIDE         1..10
FT                   /note="Venom peptide Sh41"
FT                   /evidence="ECO:0000269|PubMed:34023397"
FT                   /id="PRO_0000453647"
SQ   SEQUENCE   10 AA;  1149 MW;  4AC3736449CAB5B7 CRC64;
     DDLSDFNPKV