ID   VP5_IBDVC               Reviewed;         145 AA.
AC   P15481;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   02-JUN-2021, entry version 41.
DE   RecName: Full=Protein VP5;
GN   Name=VP5;
OS   Avian infectious bursal disease virus (strain Cu-1) (IBDV) (Gumboro disease
OS   virus).
OC   Viruses; Riboviria; Orthornavirae; Birnaviridae; Avibirnavirus.
OX   NCBI_TaxID=10998;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
OH   NCBI_TaxID=9103; Meleagris gallopavo (Wild turkey).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2552417; DOI=10.1093/nar/17.19.7982;
RA   Spies U., Mueller H., Becht H.;
RT   "Nucleotide sequence of infectious bursal disease virus genome segment A
RT   delineates two major open reading frames.";
RL   Nucleic Acids Res. 17:7982-7982(1989).
CC   -!- FUNCTION: Plays a role in the release of virion progenies by disrupting
CC       the host plasma membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host membrane; Single-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the avibirnavirus/aquabirnavirus VP5 protein
CC       family. {ECO:0000305}.
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DR   EMBL; X16107; CAA34233.1; -; Genomic_RNA.
DR   PIR; S06090; S06090.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR004284; Birna_VP5.
DR   Pfam; PF03042; Birna_VP5; 1.
PE   3: Inferred from homology;
KW   Host membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..145
FT                   /note="Protein VP5"
FT                   /id="PRO_0000221966"
FT   TOPO_DOM        1..68
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        87..145
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..37
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   145 AA;  16593 MW;  C8C2A4AD3261F25D CRC64;
     MVSRDQTNDR SDDKPARSNP TDCSVHTEPS DANNRTGVHS GRHPGEAHSQ VRDLDLQFDC
     GGHRVRANCL FPWIPWLNCG CSLHTAEQWE LQVRSDAPDC PEPTGQLQLL QASESESHSE
     VKHTSWWRLC TKRHHKRRDL PRKPE