VP5_IBDVP
ID VP5_IBDVP Reviewed; 115 AA.
AC P25222;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1992, sequence version 1.
DT 07-OCT-2020, entry version 38.
DE RecName: Full=Protein VP5;
DE Flags: Fragment;
GN Name=VP5;
OS Avian infectious bursal disease virus (strain PBG-98) (IBDV) (Gumboro
OS disease virus).
OC Viruses; Riboviria; Orthornavirae; Birnaviridae; Avibirnavirus.
OX NCBI_TaxID=11000;
OH NCBI_TaxID=9031; Gallus gallus (Chicken).
OH NCBI_TaxID=9103; Meleagris gallopavo (Wild turkey).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2161902; DOI=10.1099/0022-1317-71-6-1303;
RA Bayliss C.D., Spies U., Shaw K., Peters R.W., Papageorgiou A., Mueller H.,
RA Boursnell M.E.G.;
RT "A comparison of the sequences of segment A of four infectious bursal
RT disease virus strains and identification of a variable region in VP2.";
RL J. Gen. Virol. 71:1303-1312(1990).
CC -!- FUNCTION: Plays a role in the release of virion progenies by disrupting
CC the host plasma membrane. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host membrane; Single-pass membrane protein.
CC -!- SIMILARITY: Belongs to the avibirnavirus/aquabirnavirus VP5 protein
CC family. {ECO:0000305}.
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DR EMBL; D00868; BAA00742.1; -; Genomic_RNA.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR004284; Birna_VP5.
DR Pfam; PF03042; Birna_VP5; 1.
PE 3: Inferred from homology;
KW Host membrane; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN <1..115
FT /note="Protein VP5"
FT /id="PRO_0000221967"
FT TOPO_DOM 1..38
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 57..115
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT NON_TER 1
SQ SEQUENCE 115 AA; 13265 MW; F6B4C45488E94E1D CRC64;
DANNRTGVHS GRHPGEAHSQ VRDLDLQFDC GGHRVRANCL FPWIPWLNCG CSLHTAEQWE
LQVRSDAPDC PEPTGQLQLL QASESESHSE VKHTSWWRLC TKRHHKRRDL PRKPE