ID   VP6_AQRVC               Reviewed;         412 AA.
AC   Q8JU54;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   23-FEB-2022, entry version 45.
DE   RecName: Full=Clamp protein VP6;
GN   Name=S8;
OS   Aquareovirus C (isolate Golden shiner/USA/GSRV/1977) (AQRV-C).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Spinareovirinae; Aquareovirus.
OX   NCBI_TaxID=185783;
OH   NCBI_TaxID=28800; Notemigonus crysoleucas (Golden shiner) (Cyprinus crysoleucas).
OH   NCBI_TaxID=90988; Pimephales promelas (Fathead minnow).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=12124458; DOI=10.1099/0022-1317-83-8-1941;
RA   Attoui H., Fang Q., Mohd Jaafar F., Cantaloube J.F., Biagini P.,
RA   de Micco P., de Lamballerie X.;
RT   "Common evolutionary origin of aquareoviruses and orthoreoviruses revealed
RT   by genome characterization of Golden shiner reovirus, Grass carp reovirus,
RT   Striped bass reovirus and golden ide reovirus (genus Aquareovirus, family
RT   Reoviridae).";
RL   J. Gen. Virol. 83:1941-1951(2002).
CC   -!- FUNCTION: Located at the interface of the incomplete T=13 outer capsid
CC       and the pseudo T=2 inner capsid, 120 VP6 subunits clamp and stabilizes
CC       the inner capsid shell. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with capsid proteins VP3, VP5 and VP7.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the reoviridae clamp protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF403405; AAM92752.1; -; Genomic_RNA.
DR   RefSeq; NP_938068.1; NC_005173.1.
DR   SMR; Q8JU54; -.
DR   GeneID; 2648337; -.
DR   KEGG; vg:2648337; -.
DR   Proteomes; UP000006713; Genome.
DR   GO; GO:0039626; C:viral intermediate capsid; IEA:UniProtKB-KW.
DR   InterPro; IPR004317; Sigma_1_2_reovir.
DR   Pfam; PF03084; Sigma_1_2; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Intermediate capsid protein; Reference proteome; Virion.
FT   CHAIN           1..412
FT                   /note="Clamp protein VP6"
FT                   /id="PRO_0000404191"
SQ   SEQUENCE   412 AA;  44592 MW;  46B27A6158B1B2CD CRC64;
     MAQRQFFGLT YNFYGQPAPL FDLNDLQELA GCYARPWTSR FSHLAISTGS LPVWSARYPS
     VASRNIIVNT LLGAHLNPFA GGQVTSHQGI TWRDPVLSSL APVPAIQPPP VWAVAENVPL
     DSNNYPTYVL NLSSMWPINQ DVHIMTMWAL SDQGPIYHLE VPVDPMPAAT TAALMAYIGV
     PIAHLAQTAY RFAGQLPQSP DSTMVSTIRW LSAIWFGSLT GRLNRSRTCN GFYFEFAKPA
     LNPDQAVLKW NDGARAAPPA AAQSSYMRCI SPHWQHQIVE VAGALMSQSV TAVTGLPALI
     DEATLPAWSQ GVANLTGNGQ GVVPCLDYNP VPMAAARHLQ WRQDGLITAA QEAQLNNDYT
     AYALTIERHL TAMLVANPIA AGRMPIQPFN AADFGQAGQT AAAVALAQAM FV