ID   VP6_AQRVG               Reviewed;         413 AA.
AC   B2BNE7;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   23-FEB-2022, entry version 35.
DE   RecName: Full=Clamp protein VP6;
GN   Name=S8;
OS   Aquareovirus G (isolate American grass carp/USA/PB01-155/-) (AQRV-G).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Spinareovirinae; Aquareovirus.
OX   NCBI_TaxID=648234;
OH   NCBI_TaxID=7959; Ctenopharyngodon idella (Grass carp) (Leuciscus idella).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=18191982; DOI=10.1016/j.virol.2007.12.006;
RA   Mohd Jaafar F., Goodwin A.E., Belhouchet M., Merry G., Fang Q.,
RA   Cantaloube J.F., Biagini P., de Micco P., Mertens P.P., Attoui H.;
RT   "Complete characterisation of the American grass carp reovirus genome
RT   (genus Aquareovirus: family Reoviridae) reveals an evolutionary link
RT   between aquareoviruses and coltiviruses.";
RL   Virology 373:310-321(2008).
RN   [2]
RP   FUNCTION, AND INTERACTION WITH VP3; VP4 AND VP7.
RC   STRAIN=GCRV;
RX   PubMed=18625243; DOI=10.1016/j.jmb.2008.06.075;
RA   Cheng L., Fang Q., Shah S., Atanasov I.C., Zhou Z.H.;
RT   "Subnanometer-resolution structures of the grass carp reovirus core and
RT   virion.";
RL   J. Mol. Biol. 382:213-222(2008).
CC   -!- FUNCTION: Located at the interface of the incomplete T=13 outer capsid
CC       and the pseudo T=2 inner capsid, 120 VP6 subunits clamp and stabilize
CC       the inner capsid shell. {ECO:0000269|PubMed:18625243}.
CC   -!- SUBUNIT: Interacts with capsid proteins VP3, VP4 and VP7.
CC       {ECO:0000269|PubMed:18625243}.
CC   -!- SUBCELLULAR LOCATION: Virion.
CC   -!- SIMILARITY: Belongs to the reoviridae clamp protein family.
CC       {ECO:0000305}.
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DR   EMBL; EF589105; ABV01047.1; -; Genomic_RNA.
DR   RefSeq; YP_001837102.1; NC_010591.1.
DR   SMR; B2BNE7; -.
DR   GeneID; 6218807; -.
DR   KEGG; vg:6218807; -.
DR   Proteomes; UP000001674; Genome.
DR   GO; GO:0039626; C:viral intermediate capsid; IEA:UniProtKB-KW.
DR   InterPro; IPR004317; Sigma_1_2_reovir.
DR   Pfam; PF03084; Sigma_1_2; 1.
PE   1: Evidence at protein level;
KW   Capsid protein; Intermediate capsid protein; Reference proteome; Virion.
FT   CHAIN           1..413
FT                   /note="Clamp protein VP6"
FT                   /id="PRO_0000404192"
SQ   SEQUENCE   413 AA;  44964 MW;  7325716FF7A0A12C CRC64;
     MALRRFLRTS PITSTAQPAP LYDNQDIQDI VGAYARPWQS RFGDITITTT SAPVWSGRYP
     SVAARNIIVN TILGAHLNAF SGGVIAQYRG LTWRDNIMSS LAPPSQNPPP PAWVPAENVQ
     LDSDNYPQYA LNLSKMWSVN LDVHIMTMWA LSDYGPLYEI SVPTAPMPAM TTAALMAYIG
     CSITQLAMTA YQYAGQLPQT AAATMTTTLR WLAAIWFGSL CGVVHRNHTV NGFYFDFGKP
     GFNPDHAVLK WNDGNRAAPP AAARFRVYRV RSPHWQQMTS EVAGAILAQS VTAVAGLTAM
     FNNRGLPVWA QNIPHFTGAA AGTRVSRTYN PVTMAAARHQ NWQAAGLITA VKQAELDQQY
     TDYAQAIEVH LTAQLAANPV ANGRMPIQPF LPADFAAAGG TNQVVADARL MFP