ID   VP6_BTV13               Reviewed;         325 AA.
AC   P32934;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   02-JUN-2021, entry version 51.
DE   RecName: Full=Protein VP6;
DE   AltName: Full=Minor inner core protein VP6;
GN   Name=Segment-9;
OS   Bluetongue virus 13 (isolate USA) (BTV 13).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=33717;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1329371; DOI=10.1016/0168-1702(92)90126-t;
RA   Hwang G.-Y., Chiou J.-F., Yang Y.-Y., Li J.K.-K.;
RT   "Comparative sequence analyses of the cognate structural protein VP6 genes
RT   of five US bluetongue viruses.";
RL   Virus Res. 24:315-323(1992).
CC   -!- FUNCTION: Surrounds and interacts with the genomic dsRNA. Possesses
CC       ss- and dsRNA-binding capacity. Its hydrophilic nature and capability
CC       to bind ss- and dsRNA suggest that it interacts with BTV genomic RNA.
CC   -!- SUBCELLULAR LOCATION: Virion. Note=Inner capsid.
CC   -!- SIMILARITY: Belongs to the orbivirus VP6 family. {ECO:0000305}.
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DR   EMBL; L08671; AAA42820.1; -; Genomic_RNA.
DR   GO; GO:0039625; C:viral inner capsid; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR001399; Orbi_VP6.
DR   Pfam; PF01516; Orbi_VP6; 1.
DR   PRINTS; PR00902; VP6CAPSID.
PE   3: Inferred from homology;
KW   Capsid protein; Inner capsid protein; Virion.
FT   CHAIN           1..325
FT                   /note="Protein VP6"
FT                   /id="PRO_0000222725"
FT   REGION          1..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          174..230
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..79
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        174..229
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   325 AA;  35245 MW;  F084DB712702A334 CRC64;
     MLLAPGDVIK RSSEELKQRQ IQINLVDWTE SEGGKENKTE PKEESKAEGS KDGEGTQSES
     GQKEEGGKET KDADVDRRIH TAVGSGSSTK GPGERANENA DRGDGKVGGG GGDADAGVGA
     TGTNGRRWVV LTEEIARAIE SKYGTKIDVY RDEVPAQIIE VERSLQKELG ISREGVAEQT
     ERSRDLRRKE KNGTHAKAVE RGGRKQRKES HGDAQREGVE EEKTSEEPAR IGITIEGVMS
     QNKLLSMIGG VERKMAPIGA RESAVMLVSN SIKDVVRATA YFTAPTGDPH WKEVAREASK
     KKNILAYTST GGDAKTEFLH LIDHL