ID   VP6_MYRV9               Reviewed;         649 AA.
AC   Q65YV0;
DT   11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   02-DEC-2020, entry version 32.
DE   RecName: Full=Microtubule-associated protein VP6;
GN   Name=S6;
OS   Cryphonectria parasitica mycoreovirus 1 (strain 9B21) (CpMYRV-1).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Spinareovirinae; Mycoreovirus.
OX   NCBI_TaxID=230407;
OH   NCBI_TaxID=5116; Cryphonectria parasitica (Chestnut blight fungus) (Endothia parasitica).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=15483262; DOI=10.1099/vir.0.80293-0;
RA   Suzuki N., Supyani S., Maruyama K., Hillman B.I.;
RT   "Complete genome sequence of Mycoreovirus-1/Cp9B21, a member of a novel
RT   genus within the family Reoviridae, isolated from the chestnut blight
RT   fungus Cryphonectria parasitica.";
RL   J. Gen. Virol. 85:3437-3448(2004).
CC   -!- FUNCTION: Minor inner capsid component. Displays NTPase and RNA 5'-
CC       triphosphatase (RTPase) activities. May function as a cofactor of
CC       polymerase VP2. Associates with microtubules and plays a role in the
CC       formation, structural organization and morphology of viral inclusions,
CC       where the assembly of cores and the replication of viral RNA occur (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host cytoplasm, host
CC       cytoskeleton {ECO:0000250}.
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DR   EMBL; AB179638; BAD51416.1; -; Genomic_RNA.
DR   RefSeq; YP_001936009.1; NC_010748.1.
DR   GeneID; 6334548; -.
DR   KEGG; vg:6334548; -.
DR   Proteomes; UP000006719; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0044163; C:host cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0039625; C:viral inner capsid; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Capsid protein; Host cytoplasm; Host cytoskeleton; Inner capsid protein;
KW   Reference proteome; Virion.
FT   CHAIN           1..649
FT                   /note="Microtubule-associated protein VP6"
FT                   /id="PRO_0000403428"
SQ   SEQUENCE   649 AA;  73419 MW;  7CC42191ACF115AD CRC64;
     MELPHDKAWA YLLLTPPPLR DYFIQLPKPA TLQLALNRFA AYLEKQYLRD SLYMEKIVIG
     THYNVRKNRV LQPRIFVSPS NYTRILSTFY DHPDLIAEVL PIQHLSKSQL KRGGLTKNVL
     TSGLPEMNNE QNPYAVFEVN TIDDLKACFA FPTEWLIDIL TGRNSISLHY TIDRTSIPKW
     YAHLEARFQY SDGVTKSLTD ADLRQHYIGV QPIPVTCEEL LQKMNDASIN GNTMYRVHGY
     ESIVSSRMET VNDLVKASGK PYDVVNVQTM SSYSRSISKA INQAVTKDRH NKHVGSTKLK
     NSQGPRTTIF VMPPYITVDV VCSPMTIKPG LGPIQTKLLK SIVDQSPRRF RIAYAAKPQI
     EQDVLNKRIF STDEGPESYF QGVELLTPEA KSLLTALPQL VGTFHYEKLS YAHFPSYRLT
     AGGYNVDYFK RGVTVIVARK HGGKGMVAKL IWKLGTPVID SDDYGRIIKL VEAGLTIDDA
     VTQLFSMDYD QRNSTVSAFD EHMEMIVSQS KMKQEITYPR ASDPRITAFA DYYSKWFLKV
     PYSDYVASVK NFVTKNGLSG PNGIQSTNHY DTLVIQVHTL PEATQFLGVN NIIEVYPIID
     SYIGMILRQQ TSNTCAELLL ARYYESIHLR NFDMLPVGVV ASTLEALVG