ID   VP7_AHSV6               Reviewed;         349 AA.
AC   O71027;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Core protein VP7;
DE   AltName: Full=Capsid protein VP7;
DE   AltName: Full=VP7 antigen;
GN   Name=Segment-7;
OS   African horse sickness virus 6 (AHSV-6).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=86060;
OH   NCBI_TaxID=9838; Camelus dromedarius (Dromedary) (Arabian camel).
OH   NCBI_TaxID=9615; Canis lupus familiaris (Dog) (Canis familiaris).
OH   NCBI_TaxID=9793; Equus asinus (Donkey) (Equus africanus asinus).
OH   NCBI_TaxID=9796; Equus caballus (Horse).
OH   NCBI_TaxID=9794; Equus hemionus (Onager) (Asian wild ass).
OH   NCBI_TaxID=89252; Equus quagga burchellii (Plains zebra) (Equus burchelli).
OH   NCBI_TaxID=9785; Loxodonta africana (African elephant).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=9617769; DOI=10.1016/s0168-1702(97)00131-7;
RA   Williams C.F., Inoue T., Lucus A.-M., Zanotto P., Roy P.;
RT   "The complete sequence of four major structural proteins of African horse
RT   sickness virus serotype 6: evolutionary relationships within and between
RT   the orbiviruses.";
RL   Virus Res. 53:53-73(1998).
CC   -!- FUNCTION: Major structural core protein; binds to structural protein
CC       VP3. Constitutes the surface of the AHSV core.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the orbivirus VP7 family. {ECO:0000305}.
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DR   EMBL; AF021238; AAC40997.1; -; mRNA.
DR   SMR; O71027; -.
DR   GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR   GO; GO:0039624; C:viral outer capsid; IEA:UniProtKB-KW.
DR   GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
DR   Gene3D; 1.10.170.10; -; 1.
DR   Gene3D; 1.10.250.10; -; 1.
DR   InterPro; IPR008980; Capsid_hemagglutn.
DR   InterPro; IPR001803; Orbi_VP7_capsid.
DR   InterPro; IPR023178; Orbi_VP7_capsid_C.
DR   InterPro; IPR023176; Orbi_VP7_capsid_N.
DR   InterPro; IPR008935; Virus_capsid_a-hlx_vir.
DR   Pfam; PF00897; Orbi_VP7; 1.
DR   PRINTS; PR00903; VP7CAPSID.
DR   SUPFAM; SSF48345; SSF48345; 1.
DR   SUPFAM; SSF49818; SSF49818; 1.
PE   2: Evidence at transcript level;
KW   Capsid protein; Glycoprotein; Outer capsid protein; Virion.
FT   CHAIN           1..349
FT                   /note="Core protein VP7"
FT                   /id="PRO_0000222737"
FT   CARBOHYD        45
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   349 AA;  37828 MW;  7FE173A1D1152E2C CRC64;
     MDAIAARALS VVRACVTVTD ARVSLDPGVM ETLGIAINRY NGLTNHSVSM RPQTQAERNE
     MFFMCTDMVL AALNVQIGNI SPDYDQALAT VGALATTEIP YNVQAMNDIV RITGQMQTFG
     PSKVQTGPYA GAVEVQQSGR YYVPQGRTRG GYINSNIAEV CMDAGAAGQV NALLAPRRGD
     AVMIYFVWRP LRIFCDPQGA SLESAPGTFV TVDGVNVAAG DVVAWNTIAP VNVGNPGARR
     SILQFEVLWY TSLDRSLDTV PELAPTLTRC YAYVSPTWHA LRAVIFQQMN MQPINPPIFP
     PTERNEIVAY LLVASLADVY AALRPDFRMN GVVAPVGQIN RALVLAAYH