VP7_AHSV9
ID VP7_AHSV9 Reviewed; 349 AA.
AC Q86729; O11856;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Core protein VP7;
DE AltName: Full=Capsid protein VP7;
DE AltName: Full=VP7 antigen;
GN Name=Segment-7;
OS African horse sickness virus 9 (AHSV-9).
OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX NCBI_TaxID=10897;
OH NCBI_TaxID=9838; Camelus dromedarius (Dromedary) (Arabian camel).
OH NCBI_TaxID=9615; Canis lupus familiaris (Dog) (Canis familiaris).
OH NCBI_TaxID=9793; Equus asinus (Donkey) (Equus africanus asinus).
OH NCBI_TaxID=9796; Equus caballus (Horse).
OH NCBI_TaxID=9794; Equus hemionus (Onager) (Asian wild ass).
OH NCBI_TaxID=89252; Equus quagga burchellii (Plains zebra) (Equus burchelli).
OH NCBI_TaxID=9785; Loxodonta africana (African elephant).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=8113344; DOI=10.1016/0166-0934(93)90102-w;
RA Wade-Evans A.M., Woolhouse T., O'Hara R., Hamblin C.;
RT "The use of African horse sickness virus VP7 antigen, synthesised in
RT bacteria, and anti-VP7 monoclonal antibodies in a competitive ELISA.";
RL J. Virol. Methods 45:179-188(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=9472617; DOI=10.1099/0022-1317-79-2-333;
RA Maree S., Durbach S., Huismans H.;
RT "Intracellular production of African horsesickness virus core-like
RT particles by expression of the two major core proteins, VP3 and VP7, in
RT insect cells.";
RL J. Gen. Virol. 79:333-337(1998).
CC -!- FUNCTION: Major structural core protein; binds to structural protein
CC VP3. Constitutes the surface of the AHSV core.
CC -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the orbivirus VP7 family. {ECO:0000305}.
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DR EMBL; S69829; AAB29954.1; -; Genomic_RNA.
DR EMBL; U90337; AAC04609.1; -; Genomic_RNA.
DR SMR; Q86729; -.
DR GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR GO; GO:0039624; C:viral outer capsid; IEA:UniProtKB-KW.
DR GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
DR Gene3D; 1.10.170.10; -; 1.
DR Gene3D; 1.10.250.10; -; 1.
DR InterPro; IPR008980; Capsid_hemagglutn.
DR InterPro; IPR001803; Orbi_VP7_capsid.
DR InterPro; IPR023178; Orbi_VP7_capsid_C.
DR InterPro; IPR023176; Orbi_VP7_capsid_N.
DR InterPro; IPR008935; Virus_capsid_a-hlx_vir.
DR Pfam; PF00897; Orbi_VP7; 1.
DR PRINTS; PR00903; VP7CAPSID.
DR SUPFAM; SSF48345; SSF48345; 1.
DR SUPFAM; SSF49818; SSF49818; 1.
PE 3: Inferred from homology;
KW Capsid protein; Glycoprotein; Outer capsid protein; Virion.
FT CHAIN 1..349
FT /note="Core protein VP7"
FT /id="PRO_0000222738"
FT CARBOHYD 45
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
FT CONFLICT 5
FT /note="A -> R (in Ref. 2; AAC04609)"
FT /evidence="ECO:0000305"
FT CONFLICT 80
FT /note="V -> I (in Ref. 2; AAC04609)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 349 AA; 37814 MW; 7FE9EE9ED1137CC3 CRC64;
MDAIAARALS VVRACVTVTD ARVSLDPGVM ETLGIAINRY NGLTNHSVSM RPQTQAERNE
MFFMCTDMVL AALNVQIGNV SPDYDQALAT VGALATTEIP YNVQAMNDIV RITGQMQTFG
PSKVQTGPYA GAVEVQQSGR YYVPQGRTRG GYINSNIAEV CMDAGAAGQV NALLAPRRGD
AVMIYFVWRP LRIFCDPQGA SLESAPGTFV TVDGVNVAAG DVVAWNTIAP VNVGNPGARR
SILQFEVLWY TSLDRSLDTV PELAPTLTRC YAYVSPTWHA LRAVIFQQMN MQPINPPIFP
PTERNEIVAY LLVASLADVY AALRPDFRMN GVVAPVGQIN RALVLAAYH
