VP7_BTV10
ID VP7_BTV10 Reviewed; 349 AA.
AC P69361; P07886;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1988, sequence version 1.
DT 02-JUN-2021, entry version 76.
DE RecName: Full=Core protein VP7;
GN Name=Segment-7;
OS Bluetongue virus 10 (isolate USA) (BTV 10).
OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX NCBI_TaxID=10900;
OH NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH NCBI_TaxID=9913; Bos taurus (Bovine).
OH NCBI_TaxID=9925; Capra hircus (Goat).
OH NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH NCBI_TaxID=9940; Ovis aries (Sheep).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2831505; DOI=10.1093/nar/16.4.1620;
RA Yu Y., Fukusho A., Ritter D.G., Roy P.;
RT "Complete nucleotide sequence of the group-reactive antigen VP7 gene of
RT bluetongue virus.";
RL Nucleic Acids Res. 16:1620-1620(1988).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS).
RX PubMed=7816101; DOI=10.1038/373167a0;
RA Grimes J., Basak A.K., Roy P., Stuart D.;
RT "The crystal structure of bluetongue virus VP7.";
RL Nature 373:167-170(1995).
CC -!- FUNCTION: The VP7 protein is one of the five proteins (with VP1, VP3,
CC VP4, and VP6) which form the inner capsid of the virus.
CC -!- SUBUNIT: Homotrimer that assemble in a complex of 260 capsomers on an
CC inner scaffold composed of VP3.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the orbivirus VP7 family. {ECO:0000305}.
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DR EMBL; X06463; CAA29771.1; -; Genomic_RNA.
DR PIR; A28537; P7XR10.
DR RefSeq; YP_052967.1; NC_006022.1.
DR PDB; 1BVP; X-ray; 2.60 A; 1/2/3/4/5/6=1-349.
DR PDBsum; 1BVP; -.
DR SMR; P69361; -.
DR GeneID; 2943155; -.
DR KEGG; vg:2943155; -.
DR EvolutionaryTrace; P69361; -.
DR Proteomes; UP000007662; Genome.
DR GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR GO; GO:0039624; C:viral outer capsid; IEA:UniProtKB-KW.
DR GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
DR Gene3D; 1.10.170.10; -; 1.
DR Gene3D; 1.10.250.10; -; 1.
DR InterPro; IPR008980; Capsid_hemagglutn.
DR InterPro; IPR001803; Orbi_VP7_capsid.
DR InterPro; IPR023178; Orbi_VP7_capsid_C.
DR InterPro; IPR023176; Orbi_VP7_capsid_N.
DR InterPro; IPR008935; Virus_capsid_a-hlx_vir.
DR Pfam; PF00897; Orbi_VP7; 1.
DR PRINTS; PR00903; VP7CAPSID.
DR SUPFAM; SSF48345; SSF48345; 1.
DR SUPFAM; SSF49818; SSF49818; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Capsid protein; Glycoprotein; Outer capsid protein;
KW Reference proteome; Virion.
FT CHAIN 1..349
FT /note="Core protein VP7"
FT /id="PRO_0000222732"
FT CARBOHYD 287
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
FT HELIX 2..15
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 20..22
FT /evidence="ECO:0007829|PDB:1BVP"
FT HELIX 27..44
FT /evidence="ECO:0007829|PDB:1BVP"
FT HELIX 55..73
FT /evidence="ECO:0007829|PDB:1BVP"
FT HELIX 90..94
FT /evidence="ECO:0007829|PDB:1BVP"
FT HELIX 103..116
FT /evidence="ECO:0007829|PDB:1BVP"
FT TURN 128..131
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 133..136
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 148..155
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 158..163
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 168..170
FT /evidence="ECO:0007829|PDB:1BVP"
FT HELIX 172..174
FT /evidence="ECO:0007829|PDB:1BVP"
FT TURN 175..177
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 182..195
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 201..203
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 209..212
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 215..217
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 223..225
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 227..229
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 231..234
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 237..239
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 241..254
FT /evidence="ECO:0007829|PDB:1BVP"
FT HELIX 263..271
FT /evidence="ECO:0007829|PDB:1BVP"
FT HELIX 276..286
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 289..291
FT /evidence="ECO:0007829|PDB:1BVP"
FT STRAND 293..295
FT /evidence="ECO:0007829|PDB:1BVP"
FT HELIX 304..323
FT /evidence="ECO:0007829|PDB:1BVP"
FT HELIX 341..346
FT /evidence="ECO:0007829|PDB:1BVP"
SQ SEQUENCE 349 AA; 38548 MW; F08EDD6DD2CE86D9 CRC64;
MDTIAARALT VMRACATLQE ARIVLEANVM EILGIAINRY NGLTLRGVTM RPTSLAQRNE
MFFMCLDMML SAAGINVGPI SPDYTQHMAT IGVLATPEIP FTTEAANEIA RVTGETSTWG
PARQPYGFFL ETEETFQPGR WFMRAAQAVT AVVCGPDMIQ VSLNAGARGD VQQIFQGRND
PMMIYLVWRR IENFAMAQGN SQQTQAGVTV SVGGVDMRAG RIIAWDGQAA LHVHNPTQQN
AMVQIQVVFY ISMDKTLNQY PALTAEIFNV YSFRDHTWHG LRTAILNRTT LPNMLPPIFP
PNDRDSILTL LLLSTLADVY TVLRPEFAIH GVNPMPGPLT RAIARAAYV
