VP7_BTV13
ID VP7_BTV13 Reviewed; 349 AA.
AC P17375;
DT 01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1990, sequence version 1.
DT 02-DEC-2020, entry version 81.
DE RecName: Full=Core protein VP7;
GN Name=Segment-7;
OS Bluetongue virus 13 (isolate USA) (BTV 13).
OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX NCBI_TaxID=33717;
OH NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH NCBI_TaxID=9913; Bos taurus (Bovine).
OH NCBI_TaxID=9925; Capra hircus (Goat).
OH NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH NCBI_TaxID=9940; Ovis aries (Sheep).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2549709; DOI=10.1016/0042-6822(89)90120-7;
RA Kowalik T.F., Li J.K.-K.;
RT "Sequence analyses and structural predictions of double-stranded RNA
RT segment S1 and VP7 from United States prototype bluetongue virus serotypes
RT 13 and 10.";
RL Virology 172:189-195(1989).
CC -!- FUNCTION: The VP7 protein is one of the five proteins (with VP1, VP3,
CC VP4, and VP6) which form the inner capsid of the virus.
CC -!- SUBUNIT: Homotrimer that assemble in a complex of 260 capsomers on an
CC inner scaffold composed of VP3.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the orbivirus VP7 family. {ECO:0000305}.
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DR EMBL; J04365; AAA42833.1; -; Genomic_RNA.
DR PIR; A33385; P7XR13.
DR SMR; P17375; -.
DR GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR GO; GO:0039624; C:viral outer capsid; IEA:UniProtKB-KW.
DR GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
DR Gene3D; 1.10.170.10; -; 1.
DR Gene3D; 1.10.250.10; -; 1.
DR InterPro; IPR008980; Capsid_hemagglutn.
DR InterPro; IPR001803; Orbi_VP7_capsid.
DR InterPro; IPR023178; Orbi_VP7_capsid_C.
DR InterPro; IPR023176; Orbi_VP7_capsid_N.
DR InterPro; IPR008935; Virus_capsid_a-hlx_vir.
DR Pfam; PF00897; Orbi_VP7; 1.
DR PRINTS; PR00903; VP7CAPSID.
DR SUPFAM; SSF48345; SSF48345; 1.
DR SUPFAM; SSF49818; SSF49818; 1.
PE 3: Inferred from homology;
KW Capsid protein; Glycoprotein; Outer capsid protein; Virion.
FT CHAIN 1..349
FT /note="Core protein VP7"
FT /id="PRO_0000222734"
FT CARBOHYD 193
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
FT CARBOHYD 287
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
SQ SEQUENCE 349 AA; 38616 MW; BFDAA8D66874D5A4 CRC64;
MDTIAARALT VMRVCATLQE ARIVLEPNVM EILGIAINRY NGLTLRGVTM RPTSLAQRNE
MFFMCLDMMV SAAGINVGPI SPDYTQHMAT IGVLATPEIP FTTEAANEIA RVTGETSTWG
PARQPYGFFL ETEEVYQPGR WFMRAAQVVT PVVCGPNMVQ VSLNAGAIGD VQQIFQGRND
PMMIYLVWRR IENFSMPQGN SQRTLAGVTV SVGGVDMRAG RIIAWDGQAV LQIHNPTQQN
AMVQIQVVFY VSMDKTLNQY PALTAEIFNV YSFRDHTWHG LRTAILNRTT LPNMLPPIFP
PNDRDSVLTI LLLSTLADVY SVLRPEFAIH GVNPMPGPLT RAIARAAYA