ID   VP7_BTV17               Reviewed;         349 AA.
AC   P18609;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   02-DEC-2020, entry version 81.
DE   RecName: Full=Core protein VP7;
GN   Name=Segment-7;
OS   Bluetongue virus 17 (isolate USA) (BTV 17).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=33718;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2169609; DOI=10.1093/nar/18.17.5302;
RA   Kowalik T.F., Li J.K.-K., Chuang R.Y., Doi R.H., Osburn B.L.;
RT   "The complete nucleotide and deduced amino acid sequence of the gene
RT   encoding the major inner capsid protein, VP7 of US bluetongue virus
RT   serotype 17.";
RL   Nucleic Acids Res. 18:5302-5302(1990).
CC   -!- FUNCTION: The VP7 protein is one of the five proteins (with VP1, VP3,
CC       VP4, and VP6) which form the inner capsid of the virus.
CC   -!- SUBUNIT: Homotrimer that assemble in a complex of 260 capsomers on an
CC       inner scaffold composed of VP3.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the orbivirus VP7 family. {ECO:0000305}.
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DR   EMBL; X53693; CAA37731.1; -; Genomic_RNA.
DR   PIR; S11216; S11216.
DR   SMR; P18609; -.
DR   GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR   GO; GO:0039624; C:viral outer capsid; IEA:UniProtKB-KW.
DR   GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
DR   Gene3D; 1.10.170.10; -; 1.
DR   Gene3D; 1.10.250.10; -; 1.
DR   InterPro; IPR008980; Capsid_hemagglutn.
DR   InterPro; IPR001803; Orbi_VP7_capsid.
DR   InterPro; IPR023178; Orbi_VP7_capsid_C.
DR   InterPro; IPR023176; Orbi_VP7_capsid_N.
DR   InterPro; IPR008935; Virus_capsid_a-hlx_vir.
DR   Pfam; PF00897; Orbi_VP7; 1.
DR   PRINTS; PR00903; VP7CAPSID.
DR   SUPFAM; SSF48345; SSF48345; 1.
DR   SUPFAM; SSF49818; SSF49818; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Glycoprotein; Outer capsid protein; Virion.
FT   CHAIN           1..349
FT                   /note="Core protein VP7"
FT                   /id="PRO_0000222735"
FT   CARBOHYD        287
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   349 AA;  38562 MW;  9569431DD468A8BD CRC64;
     MDTIAARALT VMRACATLQE ARIVLEANVM EILGIAINRY NGLTLRGVTM RPTSLAQRNE
     MFFMCLDMML SATGINVGPI SPDYTQHMAT IGVLATPEIP FTTEAANEIA RVTGETSTWG
     PARQPYGFFL ETEETFQPGR WFMRAAQAVT AVVCGPDMIQ VSLNAGARGD VQQIFQGRND
     PMMIYLVWRR IENFAMAQGN SQQTQAGVTV SVGGVDMRAG RIIAWDGQAA LHVHNPTQQN
     AMVQIQVVFY ISMDKTLNQY PALTAEIFNV YSFRDHTWHG LRTAILNRTT LPNMLPPIFP
     PNDRDSILTL LPLSTLADVY TVLRPEFAIH GVNPMPGPLT RAIARAAYV