ID   VP7_BTV1A               Reviewed;         349 AA.
AC   P26560;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   02-DEC-2020, entry version 77.
DE   RecName: Full=Core protein VP7;
GN   Name=Segment-7;
OS   Bluetongue virus 1 (isolate Australia) (BTV 1).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX   NCBI_TaxID=10904;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1703371; DOI=10.1016/0042-6822(91)90082-m;
RA   Eaton B.T., Gould A.R., Hyatt A.D., Coupar B.E.H., Martyn J.C., White J.R.;
RT   "A bluetongue serogroup-reactive epitope in the amino terminal half of the
RT   major core protein VP7 is accessible on the surface of bluetongue virus
RT   particles.";
RL   Virology 180:687-696(1991).
CC   -!- FUNCTION: The VP7 protein is one of the five proteins (with VP1, VP3,
CC       VP4, and VP6) which form the inner capsid of the virus.
CC   -!- SUBUNIT: Homotrimer that assemble in a complex of 260 capsomers on an
CC       inner scaffold composed of VP3.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the orbivirus VP7 family. {ECO:0000305}.
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DR   EMBL; M63417; AAA42850.1; -; Genomic_RNA.
DR   PIR; A38551; P7XRB1.
DR   SMR; P26560; -.
DR   GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR   GO; GO:0039624; C:viral outer capsid; IEA:UniProtKB-KW.
DR   GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
DR   Gene3D; 1.10.170.10; -; 1.
DR   Gene3D; 1.10.250.10; -; 1.
DR   InterPro; IPR008980; Capsid_hemagglutn.
DR   InterPro; IPR001803; Orbi_VP7_capsid.
DR   InterPro; IPR023178; Orbi_VP7_capsid_C.
DR   InterPro; IPR023176; Orbi_VP7_capsid_N.
DR   InterPro; IPR008935; Virus_capsid_a-hlx_vir.
DR   Pfam; PF00897; Orbi_VP7; 1.
DR   PRINTS; PR00903; VP7CAPSID.
DR   SUPFAM; SSF48345; SSF48345; 1.
DR   SUPFAM; SSF49818; SSF49818; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Glycoprotein; Outer capsid protein; Virion.
FT   CHAIN           1..349
FT                   /note="Core protein VP7"
FT                   /id="PRO_0000222729"
FT   CARBOHYD        287
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   349 AA;  38531 MW;  A1E4D61B8B22C158 CRC64;
     MDTIAARALT VMRACATLQE ARIVLEANVM EILGIAINRY NGLTLRGVTM RPTSLAQRNE
     MFFMCLDMML SAAGINVGPI SPDYTQHMAT IGVLATPEIP FTTEAANEIA RVTGETSTWG
     PARQPYGFFL ETEETYQPGR WFMRAAQAVT AVVCGPDMIQ VSLNAGARGD VQQIFQGRND
     PMMIYLVWRR IENFAMAQGN SQQTLAGVTV SVGGVDMRAG RIIAWDGQAA LQIHNPTQQN
     AMVQIQVVFY ISMDKTLNQY PALTAEIFNV YSFRDHTWHG LRTAILNRTT LPNMLPPIFP
     PNDRDSILTL LLLSTLADVY TVLRPEFAIH GVNPMSGPLT RATARAAYV