VP7_BTV2A
ID VP7_BTV2A Reviewed; 349 AA.
AC P26561;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 02-DEC-2020, entry version 79.
DE RecName: Full=Core protein VP7;
GN Name=Segment-7;
OS Bluetongue virus 2 (isolate USA) (BTV 2).
OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC Reovirales; Reoviridae; Sedoreovirinae; Orbivirus.
OX NCBI_TaxID=10907;
OH NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH NCBI_TaxID=9913; Bos taurus (Bovine).
OH NCBI_TaxID=9925; Capra hircus (Goat).
OH NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH NCBI_TaxID=9940; Ovis aries (Sheep).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=1849684; DOI=10.1016/0042-6822(91)90911-t;
RA Kowalik T.F., Li J.K.-K.;
RT "Bluetongue virus evolution: sequence analyses of the genomic S1 segments
RT and major core protein VP7.";
RL Virology 181:749-755(1991).
CC -!- FUNCTION: The VP7 protein is one of the five proteins (with VP1, VP3,
CC VP4, and VP6) which form the inner capsid of the virus.
CC -!- SUBUNIT: Homotrimer that assemble in a complex of 260 capsomers on an
CC inner scaffold composed of VP3.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the orbivirus VP7 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; M64997; AAA42852.1; -; Genomic_RNA.
DR PIR; A37950; P7XRB2.
DR SMR; P26561; -.
DR GO; GO:0019031; C:viral envelope; IEA:InterPro.
DR GO; GO:0039624; C:viral outer capsid; IEA:UniProtKB-KW.
DR GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
DR Gene3D; 1.10.170.10; -; 1.
DR Gene3D; 1.10.250.10; -; 1.
DR InterPro; IPR008980; Capsid_hemagglutn.
DR InterPro; IPR001803; Orbi_VP7_capsid.
DR InterPro; IPR023178; Orbi_VP7_capsid_C.
DR InterPro; IPR023176; Orbi_VP7_capsid_N.
DR InterPro; IPR008935; Virus_capsid_a-hlx_vir.
DR Pfam; PF00897; Orbi_VP7; 1.
DR PRINTS; PR00903; VP7CAPSID.
DR SUPFAM; SSF48345; SSF48345; 1.
DR SUPFAM; SSF49818; SSF49818; 1.
PE 3: Inferred from homology;
KW Capsid protein; Glycoprotein; Outer capsid protein; Virion.
FT CHAIN 1..349
FT /note="Core protein VP7"
FT /id="PRO_0000222731"
FT CARBOHYD 287
FT /note="N-linked (GlcNAc...) asparagine; by host"
FT /evidence="ECO:0000255"
SQ SEQUENCE 349 AA; 38518 MW; A034C6D7727F96D4 CRC64;
MDTIAARALT VMRACATLQE ARIVLEANVM EILGIAINRY NGLTLRGVTM RPTSLAQRNE
MFFMCLDMML SAAGINVGPI SPDYTQHMAT IGVLATPEIP FTTEAANEIA RVTGETSTWG
PARQPYGFFL ETEETFQPGR WFMRAAQAVA AVVCGPDMIQ VSLNAGARGD VQQIFQGRND
PMMIYLVWRR IENFAMAQGN SQQTQAGVTV SVGGVDMRAG RIIAWDGQAA LHVHNPTQQN
AMVQIQVVFY ISMDKTLNQY PALTAEIFNV YSFRDHTWHG LRTAILNRTT LPNMLPPIFP
PNDRDSILTL LLLSTLADVY TVLRPEFAIH GVNPMPGPLT RAIARAAYV