ID   VP8_FDVS                Reviewed;         594 AA.
AC   Q7TF75;
DT   11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   29-SEP-2021, entry version 29.
DE   RecName: Full=Microtubule-associated protein VP8;
GN   Name=S8;
OS   Fiji disease virus (isolate Sugarcane) (FDV).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Spinareovirinae; Fijivirus.
OX   NCBI_TaxID=648172;
OH   NCBI_TaxID=4547; Saccharum officinarum (Sugarcane).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=15045559; DOI=10.1007/s00705-003-0243-1;
RA   McQualter R.B., Burns P., Smith G.R., Dale J.L., Harding R.M.;
RT   "Molecular analysis of Fiji disease virus genome segments 5, 6, 8 and 10.";
RL   Arch. Virol. 149:713-721(2004).
CC   -!- FUNCTION: Minor inner capsid component. Displays NTPase and RNA 5'-
CC       triphosphatase (RTPase) activities. May function as a cofactor of
CC       polymerase VP1. Associates with microtubules and plays a role in the
CC       formation, structural organization and morphology of viral inclusions,
CC       where the assembly of cores and the replication of viral RNA occur (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host cytoplasm, host
CC       cytoskeleton {ECO:0000250}.
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DR   EMBL; AY297693; AAP57257.1; -; Genomic_RNA.
DR   RefSeq; YP_249764.1; NC_007161.1.
DR   GeneID; 5075884; -.
DR   KEGG; vg:5075884; -.
DR   Proteomes; UP000001677; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0044163; C:host cytoskeleton; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host cytoskeleton; Reference proteome; Virion.
FT   CHAIN           1..594
FT                   /note="Microtubule-associated protein VP8"
FT                   /id="PRO_0000403400"
SQ   SEQUENCE   594 AA;  68877 MW;  A57A657811A8F44C CRC64;
     MTTGTDVRIS LRLLFYELWD NNAKLTKNKT TTPTTSKTTS KILFNSKRTT PTHGYDADYI
     AELSNNFEFA GFTAPTPHNI RKAFTRLKIM FERMNRYPDE IFLSRHRMLG FVIYQPETSG
     PIPAFHPKCK FYKLSDNHTH DEKIEIVKNH ILNGEIVKTV DLKIDQSFES YYYDKSNAQA
     SQKFLASMHT CDFSFLSFPY INDLTATELG LLPEWAAILL SYMKIINVRG IYNDVVECID
     PSQQFCVFEI IGSLTGISNG HFWSVLNDRR SMDVIAKEVE KIALDNQPFX KDGNLNHLLF
     NSINLSDPLN FNIFHYSFKL KIFPTTLNPL DDLVLLRMKD LIKAFNAGND VQVIGNKCIG
     KTRLTAELKK KYLNLLIIDS DDYGKFITLL LNNCPNLFLN NDFEINDEVF EEEIFNVTVI
     EYANVIRDGT IVIETFFERL MFEIMSLNLT NGEYDVDAIF HSFNARFHAI VNSSMIGYRL
     FFTKFRKLMF DNFNYTQVLH FVHSYSELSF YPHCVAYITL EPSYNPCCLL YKNRVKRFLS
     ITRSDKGVSS ELFLHQFYEK FTTKVNPTPV FVFRYYFGLT NGLSISELAL DENT