ID   VPB12_MYCTO             Reviewed;          75 AA.
AC   P9WJ52; L0T7Q5; P71979; Q8VJY4;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Putative antitoxin VapB12;
GN   Name=vapB12; OrderedLocusNames=MT1762;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Putative antitoxin component of a possible type II toxin-
CC       antitoxin (TA) system. The cognate toxin is VapC12 (By similarity).
CC       {ECO:0000250}.
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DR   EMBL; AE000516; AAK46034.1; -; Genomic_DNA.
DR   PIR; D70686; D70686.
DR   RefSeq; WP_003408469.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJ52; -.
DR   SMR; P9WJ52; -.
DR   EnsemblBacteria; AAK46034; AAK46034; MT1762.
DR   KEGG; mtc:MT1762; -.
DR   PATRIC; fig|83331.31.peg.1891; -.
DR   HOGENOM; CLU_176903_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR010985; Ribbon_hlx_hlx.
DR   SUPFAM; SSF47598; SSF47598; 1.
PE   3: Inferred from homology;
KW   Toxin-antitoxin system.
FT   CHAIN           1..75
FT                   /note="Putative antitoxin VapB12"
FT                   /id="PRO_0000427890"
SQ   SEQUENCE   75 AA;  8226 MW;  0DC986EAC3552F8E CRC64;
     MSAMVQIRNV PDELLHELKA RAAAQRMSLS DFLLARLAEI AEEPALDDVL DRLAALPRRD
     LGASAAELVD EARSE