ID   VPB12_SULTO             Reviewed;          79 AA.
AC   Q972K6;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 2.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Putative antitoxin VapB12 {ECO:0000255|HAMAP-Rule:MF_00794};
GN   Name=vapB12; OrderedLocusNames=STK_11255; ORFNames=STS128;
OS   Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
OS   (Sulfolobus tokodaii).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfurisphaera.
OX   NCBI_TaxID=273063;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16993 / JCM 10545 / NBRC 100140 / 7;
RX   PubMed=11572479; DOI=10.1093/dnares/8.4.123;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Jin-no K., Takahashi M., Sekine M.,
RA   Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y.,
RA   Nishijima K., Otsuka R., Nakazawa H., Takamiya M., Kato Y., Yoshizawa T.,
RA   Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K.,
RA   Masuda S., Yanagii M., Nishimura M., Yamagishi A., Oshima T., Kikuchi H.;
RT   "Complete genome sequence of an aerobic thermoacidophilic Crenarchaeon,
RT   Sulfolobus tokodaii strain7.";
RL   DNA Res. 8:123-140(2001).
RN   [2]
RP   POSSIBLE FUNCTION.
RC   STRAIN=DSM 16993 / JCM 10545 / NBRC 100140 / 7;
RX   PubMed=15718296; DOI=10.1093/nar/gki201;
RA   Pandey D.P., Gerdes K.;
RT   "Toxin-antitoxin loci are highly abundant in free-living but lost from
RT   host-associated prokaryotes.";
RL   Nucleic Acids Res. 33:966-976(2005).
CC   -!- FUNCTION: Possibly the antitoxin component of a type II toxin-antitoxin
CC       (TA) system. Its cognate toxin is VapC12 (Potential).
CC       {ECO:0000255|HAMAP-Rule:MF_00794}.
CC   -!- SIMILARITY: Belongs to the UPF0330 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00794}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB66160.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; BA000023; BAB66160.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q972K6; -.
DR   STRING; 273063.STK_11255; -.
DR   EnsemblBacteria; BAB66160; BAB66160; STK_11255.
DR   KEGG; sto:STK_11255; -.
DR   PATRIC; fig|273063.9.peg.1270; -.
DR   eggNOG; arCOG02681; Archaea.
DR   Proteomes; UP000001015; Chromosome.
DR   HAMAP; MF_00794; UPF0330; 1.
DR   InterPro; IPR003847; Put_antitoxin.
DR   Pfam; PF02697; VAPB_antitox; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..79
FT                   /note="Putative antitoxin VapB12"
FT                   /id="PRO_0000157116"
SQ   SEQUENCE   79 AA;  9454 MW;  DD14DFBA2EC6EBF8 CRC64;
     MKTIMIRDDV YKKLLEIKGD KSFSEIIEEL IEESLSVRRK KIEKYFGILN EEEARGLAKE
     IEEMRKRTDE DIARKLSNY