VPB16_MYCTU
ID VPB16_MYCTU Reviewed; 58 AA.
AC P0CW31; L0TBW6;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Putative antitoxin VapB16;
GN Name=vapB16; OrderedLocusNames=Rv2231B;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION, AND POSSIBLE FUNCTION.
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=15718296; DOI=10.1093/nar/gki201;
RA Pandey D.P., Gerdes K.;
RT "Toxin-antitoxin loci are highly abundant in free-living but lost from
RT host-associated prokaryotes.";
RL Nucleic Acids Res. 33:966-976(2005).
CC -!- FUNCTION: Putative antitoxin component of a possible type II toxin-
CC antitoxin (TA) system. The cognate toxin is VapC16.
CC {ECO:0000305|PubMed:15718296}.
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DR EMBL; AL123456; CCP45011.1; -; Genomic_DNA.
DR RefSeq; WP_003903810.1; NC_000962.3.
DR RefSeq; YP_007410918.1; NC_000962.3.
DR AlphaFoldDB; P0CW31; -.
DR SMR; P0CW31; -.
DR STRING; 83332.Rv2231B; -.
DR GeneID; 14515901; -.
DR GeneID; 55863878; -.
DR KEGG; mtu:Rv2231B; -.
DR TubercuList; Rv2231B; -.
DR Proteomes; UP000001584; Chromosome.
PE 4: Predicted;
KW Reference proteome; Toxin-antitoxin system.
FT CHAIN 1..58
FT /note="Putative antitoxin VapB16"
FT /id="PRO_0000408062"
SQ SEQUENCE 58 AA; 6509 MW; 9C7271D15B98D17D CRC64;
MALWYQAMIA KFGEQVVDAK VWAPAKRVGV HEAKTRLSEL LRLVYGGQRL RLPAAASR