VPB18_MYCTO
ID VPB18_MYCTO Reviewed; 92 AA.
AC P9WJ46; L0T9Y1; P95008; Q7D6Y2;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 30.
DE RecName: Full=Putative antitoxin VapB18;
GN Name=vapB18; OrderedLocusNames=MT2621;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- FUNCTION: Putative antitoxin component of a possible type II toxin-
CC antitoxin (TA) system. The cognate toxin is VapC18 (By similarity).
CC {ECO:0000250}.
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DR EMBL; AE000516; AAK46932.1; -; Genomic_DNA.
DR PIR; E70659; E70659.
DR RefSeq; WP_003901422.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WJ46; -.
DR SMR; P9WJ46; -.
DR EnsemblBacteria; AAK46932; AAK46932; MT2621.
DR GeneID; 45426547; -.
DR KEGG; mtc:MT2621; -.
DR PATRIC; fig|83331.31.peg.2827; -.
DR HOGENOM; CLU_2410123_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR InterPro; IPR019239; VapB_antitoxin.
DR Pfam; PF09957; VapB_antitoxin; 1.
PE 3: Inferred from homology;
KW Toxin-antitoxin system.
FT CHAIN 1..92
FT /note="Putative antitoxin VapB18"
FT /id="PRO_0000427893"
SQ SEQUENCE 92 AA; 10126 MW; 227BB7A3BB7C76DB CRC64;
MSTTIVAGVI QGHLPVILPT RRRARDLGHT TALFRAQTLQ CIYLSIEYLY VCSMSRRTTI
DIDDILLARA QAALGTTGLK DRVDAALRAA VR