VPB20_MYCTO
ID VPB20_MYCTO Reviewed; 81 AA.
AC P9WJ44; L0TA46; P95003; Q7D6X8;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Antitoxin VapB20;
GN Name=vapB20; OrderedLocusNames=MT2627;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC Neutralizes the toxic effect of cognate toxin VapC20.
CC {ECO:0000250|UniProtKB:P9WJ45}.
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DR EMBL; AE000516; AAK46938.1; -; Genomic_DNA.
DR PIR; B70660; B70660.
DR RefSeq; WP_003413183.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WJ44; -.
DR SMR; P9WJ44; -.
DR EnsemblBacteria; AAK46938; AAK46938; MT2627.
DR KEGG; mtc:MT2627; -.
DR PATRIC; fig|83331.31.peg.2833; -.
DR HOGENOM; CLU_2700760_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR002145; CopG.
DR Pfam; PF01402; RHH_1; 1.
PE 3: Inferred from homology;
KW DNA-binding; Toxin-antitoxin system.
FT CHAIN 1..81
FT /note="Antitoxin VapB20"
FT /id="PRO_0000427894"
SQ SEQUENCE 81 AA; 9098 MW; 75DA114C988E4DD3 CRC64;
MLVAYICHVK RLQIYIDEDV DRALAVEARR RRTSKAALIR EYVAEHLRQP GPDPVDAFVG
SFVGEADLSA SVDDVVYGKH E