VPB23_MYCTU
ID VPB23_MYCTU Reviewed; 82 AA.
AC P0CW32; L0TCG7;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Putative antitoxin VapB23;
GN Name=vapB23; OrderedLocusNames=Rv2862A;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION, AND POSSIBLE FUNCTION.
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=15718296; DOI=10.1093/nar/gki201;
RA Pandey D.P., Gerdes K.;
RT "Toxin-antitoxin loci are highly abundant in free-living but lost from
RT host-associated prokaryotes.";
RL Nucleic Acids Res. 33:966-976(2005).
CC -!- FUNCTION: Putative antitoxin component of a possible type II toxin-
CC antitoxin (TA) system. The cognate toxin is VapC23.
CC {ECO:0000305|PubMed:15718296}.
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DR EMBL; AL123456; CCP45664.1; -; Genomic_DNA.
DR RefSeq; WP_003913411.1; NZ_NVQJ01000006.1.
DR RefSeq; YP_007411570.1; NC_000962.3.
DR AlphaFoldDB; P0CW32; -.
DR SMR; P0CW32; -.
DR STRING; 83332.Rv2862A; -.
DR PRIDE; P0CW32; -.
DR GeneID; 14515870; -.
DR GeneID; 45426850; -.
DR KEGG; mtu:Rv2862A; -.
DR PATRIC; fig|83332.111.peg.3184; -.
DR TubercuList; Rv2862A; -.
DR Proteomes; UP000001584; Chromosome.
PE 4: Predicted;
KW Reference proteome; Toxin-antitoxin system.
FT CHAIN 1..82
FT /note="Putative antitoxin VapB23"
FT /id="PRO_0000408068"
SQ SEQUENCE 82 AA; 9533 MW; F822AE67EEABAF78 CRC64;
MLSDEEREAF RQQAAAQQMS LSNWLRQAGL RQLEAQRQRP LRTAQELREF FASRPDETGA
EPDWQAHLQV MAESRRRGLP AP