VPB24_MYCTU
ID VPB24_MYCTU Reviewed; 77 AA.
AC P9WJ41; L0T4S6; O53662; Q7DA72;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Putative antitoxin VapB24;
GN Name=vapB24; OrderedLocusNames=Rv0239;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP POSSIBLE FUNCTION.
RC STRAIN=ATCC 35801 / TMC 107 / Erdman;
RX PubMed=20011113; DOI=10.1371/journal.pgen.1000767;
RA Ramage H.R., Connolly L.E., Cox J.S.;
RT "Comprehensive functional analysis of Mycobacterium tuberculosis toxin-
RT antitoxin systems: implications for pathogenesis, stress responses, and
RT evolution.";
RL PLoS Genet. 5:E1000767-E1000767(2009).
CC -!- FUNCTION: Possibly the antitoxin component of a type II toxin-antitoxin
CC (TA) system. Its cognate toxin is VapC24.
CC {ECO:0000305|PubMed:20011113}.
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DR EMBL; AL123456; CCP42968.1; -; Genomic_DNA.
DR PIR; C70938; C70938.
DR RefSeq; NP_214753.1; NC_000962.3.
DR RefSeq; WP_003401300.1; NZ_NVQJ01000001.1.
DR AlphaFoldDB; P9WJ41; -.
DR SMR; P9WJ41; -.
DR STRING; 83332.Rv0239; -.
DR PaxDb; P9WJ41; -.
DR DNASU; 886689; -.
DR GeneID; 45424212; -.
DR GeneID; 886689; -.
DR KEGG; mtu:Rv0239; -.
DR TubercuList; Rv0239; -.
DR OMA; RVPEETW; -.
DR Proteomes; UP000001584; Chromosome.
PE 4: Predicted;
KW Reference proteome; Toxin-antitoxin system.
FT CHAIN 1..77
FT /note="Putative antitoxin VapB24"
FT /id="PRO_0000408069"
SQ SEQUENCE 77 AA; 9138 MW; BB4BA87DD9CAD7FE CRC64;
MIRTQVQLPD ELYRDAKRVA HEHEMTLAEV VRRGLEHMVR IYPRRDAASD TWQPPTPRRL
GPFRASEETW RELANEA