ID   VPB34_MYCTU             Reviewed;          70 AA.
AC   P9WJ31; L0T7J3; O08147; P71998; Q7D818;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 29.
DE   RecName: Full=Putative antitoxin VapB34;
GN   Name=vapB34; OrderedLocusNames=Rv1740;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   POSSIBLE FUNCTION.
RC   STRAIN=ATCC 35801 / TMC 107 / Erdman;
RX   PubMed=20011113; DOI=10.1371/journal.pgen.1000767;
RA   Ramage H.R., Connolly L.E., Cox J.S.;
RT   "Comprehensive functional analysis of Mycobacterium tuberculosis toxin-
RT   antitoxin systems: implications for pathogenesis, stress responses, and
RT   evolution.";
RL   PLoS Genet. 5:E1000767-E1000767(2009).
CC   -!- FUNCTION: Antitoxin component of a possible type II toxin-antitoxin
CC       (TA) system. The cognate toxin is VapC34.
CC       {ECO:0000305|PubMed:20011113}.
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DR   EMBL; AL123456; CCP44506.1; -; Genomic_DNA.
DR   PIR; E70985; E70985.
DR   RefSeq; NP_216256.1; NC_000962.3.
DR   RefSeq; WP_003408528.1; NZ_NVQJ01000010.1.
DR   AlphaFoldDB; P9WJ31; -.
DR   SMR; P9WJ31; -.
DR   STRING; 83332.Rv1740; -.
DR   PaxDb; P9WJ31; -.
DR   GeneID; 885226; -.
DR   KEGG; mtu:Rv1740; -.
DR   TubercuList; Rv1740; -.
DR   eggNOG; COG4423; Bacteria.
DR   OMA; IRRRWSE; -.
DR   PhylomeDB; P9WJ31; -.
DR   Proteomes; UP000001584; Chromosome.
DR   InterPro; IPR011660; VapB-like.
DR   Pfam; PF07704; PSK_trans_fac; 1.
PE   4: Predicted;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..70
FT                   /note="Putative antitoxin VapB34"
FT                   /id="PRO_0000413610"
SQ   SEQUENCE   70 AA;  7608 MW;  B39060532B281DAD CRC64;
     MELAARMGET LTQAVVVAVR EQLARRTGRT RSISLREELA AIGRRCAALP VLDTRAADTI
     LGYDERGLPA