ID   VPB35_MYCTO             Reviewed;          90 AA.
AC   P9WF16; F2GGQ3; P0CW28; Q8VJT6;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Antitoxin VapB35;
GN   Name=vapB35; OrderedLocusNames=MT2013;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       Neutralizes the effect of cognate toxin VapC35 (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phD/YefM antitoxin family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46285.1; -; Genomic_DNA.
DR   RefSeq; WP_003899100.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WF16; -.
DR   SMR; P9WF16; -.
DR   EnsemblBacteria; AAK46285; AAK46285; MT2013.
DR   GeneID; 45425933; -.
DR   KEGG; mtc:MT2013; -.
DR   PATRIC; fig|83331.31.peg.2168; -.
DR   HOGENOM; CLU_163140_2_2_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   InterPro; IPR036165; YefM-like_sf.
DR   SUPFAM; SSF143120; SSF143120; 1.
PE   3: Inferred from homology;
KW   Toxin-antitoxin system.
FT   CHAIN           1..90
FT                   /note="Antitoxin VapB35"
FT                   /id="PRO_0000428617"
FT   REGION          53..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   90 AA;  9818 MW;  F5552E383F018AE7 CRC64;
     MNEVSIRTLN QETSKVLARV KRGEEINLTE RGKVIARIIP ASAGPLDSLI STGSVQPARV
     HGPAPRPTIP MRGGLDSGTL LERMRAEERY