ID   VPB37_MYCTU             Reviewed;          84 AA.
AC   P9WJ27; L0T8P1; O53502; Q7D7I6;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Putative antitoxin VapB37;
GN   Name=vapB37; OrderedLocusNames=Rv2104c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   POSSIBLE FUNCTION.
RC   STRAIN=ATCC 35801 / TMC 107 / Erdman;
RX   PubMed=20011113; DOI=10.1371/journal.pgen.1000767;
RA   Ramage H.R., Connolly L.E., Cox J.S.;
RT   "Comprehensive functional analysis of Mycobacterium tuberculosis toxin-
RT   antitoxin systems: implications for pathogenesis, stress responses, and
RT   evolution.";
RL   PLoS Genet. 5:E1000767-E1000767(2009).
CC   -!- FUNCTION: Probable antitoxin component of a type II toxin-antitoxin
CC       (TA) system. Its putative cognate toxin is VapC37.
CC       {ECO:0000305|PubMed:20011113}.
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DR   EMBL; AL123456; CCP44879.1; -; Genomic_DNA.
DR   PIR; E70841; E70841.
DR   RefSeq; NP_216620.1; NC_000962.3.
DR   RefSeq; WP_003410814.1; NZ_NVQJ01000084.1.
DR   AlphaFoldDB; P9WJ27; -.
DR   SMR; P9WJ27; -.
DR   PaxDb; P9WJ27; -.
DR   DNASU; 888014; -.
DR   GeneID; 45426080; -.
DR   GeneID; 888014; -.
DR   KEGG; mtu:Rv2104c; -.
DR   TubercuList; Rv2104c; -.
DR   eggNOG; ENOG5033GPM; Bacteria.
DR   OMA; RATPQFQ; -.
DR   PhylomeDB; P9WJ27; -.
DR   Proteomes; UP000001584; Chromosome.
PE   4: Predicted;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..84
FT                   /note="Putative antitoxin VapB37"
FT                   /id="PRO_0000408079"
SQ   SEQUENCE   84 AA;  9418 MW;  C9677AA6356C04A0 CRC64;
     MRTTVTLDDD VEQLVRRRMA ERQVSFKKAL NDAIRDGASG RPAPSHFSTR TADLGVPAVN
     LDRALQLAAD LEDEELVRRQ RRGS