ID   VPB44_MYCTU             Reviewed;          80 AA.
AC   P9WJ17; L0TDT2; O53373; Q7D5P9;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Putative antitoxin VapB44;
GN   Name=vapB44; OrderedLocusNames=Rv3321c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   POSSIBLE FUNCTION.
RC   STRAIN=ATCC 35801 / TMC 107 / Erdman;
RX   PubMed=20011113; DOI=10.1371/journal.pgen.1000767;
RA   Ramage H.R., Connolly L.E., Cox J.S.;
RT   "Comprehensive functional analysis of Mycobacterium tuberculosis toxin-
RT   antitoxin systems: implications for pathogenesis, stress responses, and
RT   evolution.";
RL   PLoS Genet. 5:E1000767-E1000767(2009).
CC   -!- FUNCTION: Possibly the antitoxin component of a type II toxin-antitoxin
CC       (TA) system. Its cognate toxin is VapC44.
CC       {ECO:0000305|PubMed:20011113}.
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DR   EMBL; AL123456; CCP46141.1; -; Genomic_DNA.
DR   PIR; H70843; H70843.
DR   RefSeq; NP_217838.1; NC_000962.3.
DR   RefSeq; WP_003417286.1; NZ_NVQJ01000003.1.
DR   AlphaFoldDB; P9WJ17; -.
DR   SMR; P9WJ17; -.
DR   STRING; 83332.Rv3321c; -.
DR   PaxDb; P9WJ17; -.
DR   DNASU; 887577; -.
DR   GeneID; 45427321; -.
DR   GeneID; 887577; -.
DR   KEGG; mtu:Rv3321c; -.
DR   TubercuList; Rv3321c; -.
DR   eggNOG; ENOG5033H2H; Bacteria.
DR   OMA; FIVRTTI; -.
DR   PhylomeDB; P9WJ17; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0052572; P:response to host immune response; IEP:MTBBASE.
PE   4: Predicted;
KW   Reference proteome; Toxin-antitoxin system.
FT   CHAIN           1..80
FT                   /note="Putative antitoxin VapB44"
FT                   /id="PRO_0000408084"
FT   REGION          39..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   80 AA;  8850 MW;  EBCAF8D6A242D29B CRC64;
     MRTTLSIDDD VLLAVKERAR REKRTAGEIL SDLARQALTN QNPQPAASQE DAFHGFEPLP
     HRGGAVSNAL IDRLRDEEAV