ID   VPB45_MYCTO             Reviewed;         150 AA.
AC   P9WF14; L0TBS0; O53331; Q7D5Z5;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Putative antitoxin VapB45;
GN   Name=vapB45; OrderedLocusNames=MT3272;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Possibly the antitoxin component of a type II toxin-antitoxin
CC       (TA) system. Its cognate toxin is VapC45 (Potential). {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the phD/YefM antitoxin family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK47612.1; -; Genomic_DNA.
DR   PIR; C70949; C70949.
DR   RefSeq; WP_003899953.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WF14; -.
DR   SMR; P9WF14; -.
DR   EnsemblBacteria; AAK47612; AAK47612; MT3272.
DR   GeneID; 45427170; -.
DR   KEGG; mtc:MT3272; -.
DR   PATRIC; fig|83331.31.peg.3522; -.
DR   HOGENOM; CLU_1738457_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   InterPro; IPR006442; Antitoxin_Phd/YefM.
DR   InterPro; IPR036165; YefM-like_sf.
DR   Pfam; PF02604; PhdYeFM_antitox; 1.
DR   SUPFAM; SSF143120; SSF143120; 1.
PE   3: Inferred from homology;
KW   Toxin-antitoxin system.
FT   CHAIN           1..150
FT                   /note="Putative antitoxin VapB45"
FT                   /id="PRO_0000428618"
FT   REGION          124..150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   150 AA;  16799 MW;  E987C6E7708019C5 CRC64;
     MQLGRKVTSH HDIDRFGVAS TADESVYRPL PPRLRLAQVN LSRRRCRTQS DMYKSRFSEC
     TVQSVDVSVT ELRAHLSDWL DRARAGGEVV ITERGIPIAR LAALDSTDTL ERLTAEGVIG
     KATAQRPVAA GRPRPRPQRP VSDRVSDQRR